플루오로아세트아미드 C화학적 특성, 용도, 생산
개요
Fluoroacetamide is an odourless, tasteless, white, crystalline water soluble. It is a fluorinated
amide and reacts with azo and diazo compounds to generate toxic gases. Flammable
gases are formed by the reaction of organic amides/imides with strong reducing agents.
Fluoroacetamide is used as a rodenticide and insecticide to control rabbits but is dangerous
for other species of pests, farm livestock, and humans. Fluoroacetamide is a noncombustible
substance itself and does not burn but may decompose upon heating to
produce irritating, corrosive, and/or toxic fumes. On decomposition, fluoroacetamide
releases nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon
dioxide, HF gas, and nitrogen gas.
화학적 성질
Fluoroacetamide is a colorless, crystalline
solid.
용도
Rodenticide. Insecticide proposed mainly for use on fruits to combat scale insects, aphids, and mites.
정의
ChEBI: Acetamide substituted at C-2 by a fluorine atom.
생산 방법
Fluoroacetamide is produced by reaction of α-chloroacetamide
with potassium fluoride in tetrachloroethylene
at elevated temperature.
일반 설명
Colorless crystalline powder. Used as a rodenticide. Highly toxic.
공기와 물의 반응
Very soluble in water [Farm Chemicals]
반응 프로필
FLUOROACETAMIDE is a fluorinated amide. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
위험도
Extremely toxic; poison; mutagen.
건강위험
FLUOROACETAMIDE is super toxic; probable oral lethal dose in humans is less than 5 mg/kg, or a taste (less than 7 drops) for a 150-lb. person. Chemically inhibits oxygen metabolism by cells with critical damage occurring to the heart, brain, and lungs resulting in heart failure, respiratory arrest, convulsions, and death.
화재위험
Emits very toxic fumes of fluorine containing compounds and nitrogen oxides when heated to decomposition. Avoid decomposing heat.
Safety Profile
A human poison by an
unspecified route. Poison experimentally by
ingestion, skin contact, intraperitoneal,
subcutaneous, and intravenous routes.
Human systemic effects by unspecified
route: convulsions, coma, nausea and
vomiting. Experimental reproductive effects.
Mutation data reported. Used as an
insecticide and rodenticide. When heated to
decomposition it emits very toxic fumes of
Fand NOx. See also FLUORIDES.
잠재적 노출
This material is an organofluorine
rodenticide; insecticide proposed mainly for use on fruits to
combat scale insects, aphids, and mites. Use is largely
restricted to licensed pest control operators.
운송 방법
UN2811 Toxic solids, organic, n.o.s., Hazard
Class: 6.1; Labels: 6.1-Poisonous materials, Technical
Name Required.
Purification Methods
Crystallise fluoroacetamide from chloroform and dry it in a vacuum. [Beilstein 2 IV 454.]
비 호환성
Incompatible with oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates, chlorine,
bromine, fluorine, etc.); contact may cause fires or explo sions. Keep away from alkaline materials, strong bases,
strong acids, oxoacids, epoxides.
폐기물 처리
Consult with environmental
regulatory agencies for guidance on acceptable disposal
practices. Generators of waste containing this contaminant
(≥100 kg/mo) must conform with EPA regulations govern ing storage, transportation, treatment, and waste disposal.
플루오로아세트아미드 준비 용품 및 원자재
원자재
준비 용품
