5-(히드록시메틸)우라실
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5-(히드록시메틸)우라실 속성
- 녹는점
- >300 °C(lit.)
- 밀도
- 1.401±0.06 g/cm3(Predicted)
- 저장 조건
- Sealed in dry,Room Temperature
- 용해도
- DMSO(약간 용해됨, 가열), 메탄올(약간 용해됨, 가열), 물(약간 용해됨, 가열)
- 산도 계수 (pKa)
- 8.46±0.10(Predicted)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 하얀색
- 수용성
- 물에 용해됩니다. (50 g/L), 20°C, DMSO, 디메틸 포름아미드 또는 100% 에탄올.
- BRN
- 125482
- InChI
- InChI=1S/C5H6N2O3/c8-2-3-1-6-5(10)7-4(3)9/h1,8H,2H2,(H2,6,7,9,10)
- InChIKey
- JDBGXEHEIRGOBU-UHFFFAOYSA-N
- SMILES
- C1(=O)NC=C(CO)C(=O)N1
- CAS 데이터베이스
- 4433-40-3(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
5-(히드록시메틸)우라실 C화학적 특성, 용도, 생산
개요
5-Hydroxymethyluracil is a product of oxidative damage to DNA, predominantly by hydroxyl radical via the Fenton reaction. It can be used as a potential epigenetic mark enhancing or inhibiting transcription with bacterial RNA polymerase.화학적 성질
White Powder용도
5-Hydroxymethyluracil (cas# 4433-40-3) is a compound useful in organic synthesis.정의
ChEBI: 5-hydroxymethyluracil is a primary alcohol that is uracil bearing a hydroxymethyl substituent at the 5-position. It has a role as a human metabolite. It is a primary alcohol and a pyrimidone. It derives from a uracil.Biosynthesis
5-Hydroxymethyluracil is produced by the enzyme thymine dioxygenase (EC 1.14.11.6) which catalyzes the chemical reaction thymine + 2-oxoglutarate + O2 <-> 5-hydroxymethyluracil + succinate + CO2.The 3 substrates of this enzyme are thymine, 2-oxoglutarate, and O2, whereas its 3 products are 5-hydroxymethyluracil, succinate, and CO2. The 5hmU base can also be generated by oxidation/hydroxylation of thymine by the Ten-Eleven-Translocation (TET) proteins or result from deamination of 5hmC. DNA containing 5hmU has been reported to be more flexible and hydrophilic.
생명 공학 생산
5-Hydroxymethyluracil (5hmU) is a thymine base modification found in the genomic DNA of diverse organisms ranging from bacteriophages to mammals.5-(히드록시메틸)우라실 준비 용품 및 원자재
원자재
수산화칼륨
포르말린
염산
우라실
4(3H)-Pyrimidinone, 2-(ethylthio)-5-(isocyanatomethyl)-
2,4(1H,3H)-Pyrimidinedione, dihydro-5,6-dihydroxy-
Propanamide, N-[(formylamino)carbonyl]-2-oxo-
5-(2-Hydroxy-ethoxymethyl)-1H-pyrimidine-2,4-dione
2,4(1H,3H)-Pyrimidinedione, 5-(aminomethyl)- (9CI)
2,4(1H,3H)-Pyrimidinedione, 5-(isocyanatomethyl)-
5-hydroperoxymethyl-2'-deoxyuridine
Thymidine, α-(phenylseleno)-
5-(CHLOROMETHYL)URACIL
2,4,5-TRIHYDROXYPYRIMIDINE
2(1H)-Pyrimidinone, 4-amino-5-hydroxy- (9CI)
DIHYDROTHYMINE
준비 용품
5-(히드록시메틸)우라실 공급 업체
글로벌( 223)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Sense Chemicals (Shanghai) Co., Ltd. | +86-21-52751036; +8613818977689 |
david.dai@sensechemicals.com | China | 224 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 |
sales@amoychem.com | China | 6387 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-18789408387 |
1057@dideu.com | China | 3586 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 |
contact@fuxinpharm.com | China | 10297 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 |
contact@trustwe.com | China | 5738 | 58 |
5-(히드록시메틸)우라실 관련 검색:
실버(I) 설파다이아진 모노메틸올 우레아 티민 시토신 술파디아진 우라실 플루시토신 5-(히드록시메틸)우라실
Pseudouridine
5-CARBETHOXYURACIL
2,4-Dihydroxypyrimidine-5-carboxylic acid
5-HYDROXYMETHYL-2'-DEOXYURIDINE
2,4-DIMETHOXY-5-PYRIMIDINECARBOXYLIC ACID
4-methyl-5-hydroxymethyluraci
AURORA KA-4986
methyl 6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
AURORA KA-548
AURORA KA-4984