D-gamma-Tocotrienol

D-gamma-Tocotrienol 구조식 이미지
카스 번호:
14101-61-2
상품명:
D-gamma-Tocotrienol
동의어(영문):
γ-Tocotrienol;D-G-TOCOTRIENOL;Gama-Tocotrienol;D-GAMMA-TOCOTRIENOL;(R)-gamma-Tocotrienol;(-)-gamma-Tocotrienol;TOCOTRIENOL, D-GAMMA-;Senecionine Impurity 4;7,8-Dimethyltocotrienol;D-gamma-Tocotrienol (P)
CBNumber:
CB71241238
분자식:
C28H42O2
포뮬러 무게:
410.63
MOL 파일:
14101-61-2.mol
MSDS 파일:
SDS

D-gamma-Tocotrienol 속성

끓는 점
530.8±49.0 °C(Predicted)
밀도
0.964±0.06 g/cm3(Predicted)
저장 조건
−20°C
용해도
클로로포름(약간 용해됨), 에틸아세테이트(약간 용해됨), 메탄올(약간 용해됨)
용해도
클로로포름(약간), 에틸아세테이트(약간), 메탄올(약간)에 용해됨
산도 계수 (pKa)
11.05±0.40(Predicted)
색상
매우 진한 노란색
안정성
감광성
LogP
10.300 (est)

안전

WGK 독일 2

D-gamma-Tocotrienol C화학적 특성, 용도, 생산

개요

γ-Tocotrienol is a form of vitamin E that has been found in rice bran and has diverse biological activities. It reduces cell death induced by hydrogen peroxide, paraquat, S-nitrocysteine, SIN-1 , or L-buthionine-(S,R)-sulfoximine (BSO; ) in rat striatal cultures when used at concentrations ranging from 0.1 to 10 μM. γ-Tocotrienol (20 μM) induces apoptosis in malignant sympathoadrenal (+SA) mouse mammary epithelial cells. In vivo, γ-tocotrienol (15, 30, and 150 mg/kg) reduces blood pressure and plasma lipid peroxide levels in spontaneously hypertensive rats. [Matreya, LLC. Catalog No. 2111]

화학적 성질

g:d:aTocotrienol 1.6:0.4:1

용도

γ-Tocotrienol exhibits antioxidant properties and belongs to the vitamin E family. It is naturally found in wheat germ oil and bran. In addition, α-tocopherol and γ-tocotrienol derivatives are potential lead compounds for developing?anticancer and?antiproliferative agents against?MCF-7 and MDA-MB-231 breast cancer cells and the A549 lung cancer cells.

정의

ChEBI: A tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2, 7 and 8 and a farnesyl chain at position 2.

D-gamma-Tocotrienol 준비 용품 및 원자재

원자재

준비 용품


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