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Tandospirone citrate

Tandospirone citrate 구조식 이미지

카스 번호:: 112457-95-1

상품명:: Tandospirone citrate

동의어(영문):: andospironecitrate;SM 3997;Methanospirone;SM-3997 citrate;tandospirone citrate;Tandopsirone citrate;Tandospirone-d8 Citrate;Tandospirone citrate (SM 3997);(3aα,4β,7β,7aα)-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dione·citric acid;SM3997,SM-3997,Tandospirone,Tandospirone citrate,Inhibitor,Serotonin Receptor,SM 3997,5-hydroxytryptamine Receptor,inhibit,5-HT Receptor

CBNumber:: CB71270043

분자식:: C21H29N5O2.C6H8O7

포뮬러 무게:: 575.615

MOL 파일:: 112457-95-1.mol

속성

안전

용도

공급 업체 112

Tandospirone citrate 속성

녹는점: 169.5-170°

저장 조건: Inert atmosphere,Store in freezer, under -20°C

수용성: Water: 10.4 mg/mL (18.07 mM)

InChIKey: DMLGUJHNIWGCKM-DPFKZJTMNA-N

SMILES: [C@@]12(C(=O)N(CCCCN3CCN(C4=NC=CC=N4)CC3)C(=O)[C@]1([C@@]1(CC[C@]2(C1)[H])[H])[H])[H].C(O)(C(=O)O)(CC(=O)O)CC(=O)O |&1:0,22,23,26,r|

안전

Tandospirone citrate C화학적 특성, 용도, 생산

용도

Tandospirone citrate is a potent 5-HT1A partial agonist with a Ki value of 27 nM. Tandospirone citrate is approximately two to three orders of magnitude less potent at 5-HT2, 5-HT1C, alpha 1-adrenergic, alpha 2-adrenergic, and dopamine D1 and D2 receptors (Ki values ranging from 1300 to 41000 nM).
Anti-anxiety agent.

Pharmacology

Tandospirone citrate is a partial agonist of the 5-hydroxytryptamine type 1A (5-HT1A) receptor,which selectively binds to the 5-HT1A receptor in the brain. The anti-anxiety effect is exerted by inhibiting the activities of the 5-HT1A system via selectively stimulating the 5-HT1A receptor widely distributed in these sites.

부작용

The most common adverse reactions to Tandospirone citrate include drowsiness, dizziness, headache, nausea, malaise, rash, urticaria and pruritus. In addition, there are some symptoms that require special attention, such as those related to hepatic insufficiency and jaundice: general malaise, loss of appetite, yellowing of the skin and whites of the eyes. Excitement, sweating and trembling associated with serotonin syndrome. Fever, impaired consciousness, sweating associated with malignant syndrome. These symptoms are rarely considered initial symptoms of the indicated adverse reaction. However, if you experience discomfort, contact your doctor immediately.

Tandospirone citrate 준비 용품 및 원자재

원자재

Tandospirone 시트르산

준비 용품

Tandospirone citrate 공급 업체

글로벌( 112)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Chengdu Aupone Pharmaceutical Co.Ltd.	+86-28-+86-28-87843998-6060-6060 +8618631098571	lijiaqi@aupone.com	China	43	58
Biopole Pharmatech Co., Ltd.	+8615151475053	biopole@163.com	China	37	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	11013	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
Shanxi Xuanran Import and Export Trade Co., Ltd.	+8617735180244	mike_yan@xuanranglobal.com	CHINA	4022	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9923	58
changzhou huayang technology co., ltd	+8615250961469	2571773637@qq.com	China	9821	58

Tandospirone citrate 관련 검색:

구연산 암모늄, 삼염기 (2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid LCZ 696 Impurity C LCZ 696 Impurity B rac-Lipoic Acid Impurity 1 (S-Oxide) 3-(3-fluorobenzyl)-4-(3-fluoro-benzyloxy)benzaldehyde 4-Benzyl Albuterol [R(R*,R*]-2-amino-1-[p-(methylsulphonyl)phenyl]propane-1,3-diol PWKRNMKZGWGSDV-UHFFFAOYSA-N Tandospirone citrate Tandospirone 1,2-Cyclohexanedicarboximide cis-Octahydroisoindole 2-AZACYCLOOCTANONE cis-7-Azabicyclo[3.3.0]octane PIPERAZINE DL-MALATE N-Butyl-2-methyl-succinimide 4-AZA-TRICYCLO[5.2.1.0 2,6 ]DECANE