ailanthone

ailanthone 구조식 이미지
카스 번호:
981-15-7
상품명:
ailanthone
동의어(영문):
ailanthone;Δ13-Dehydrochaparrinone;13,21-Didehydrochaparrinone;2H-1,11c-(Epoxymethano)phenanthro[10,1-bc]pyran-5,10(3H,6aH);(1beta,11alpha,12alpha)-1,11,12-trihydroxy-11,20-epoxypicras...;11β,20-Epoxy-1β,11,12α-trihydroxypicrasa-3,13(21)-diene-2,16-dione;(1β,11β,12α)-11,20-Epoxy-1,11,12-trihydroxypicrasa-3,13(21)-diene-2,16-dione;Picrasa-3,13(21)-diene-2,16-dione,11,20-epoxy-1,11,12-trihydroxy-, (1b,11b,12a)-;Picrasa-3,13(21)-diene-2,16-dione, 11,20-epoxy-1,11,12-trihydroxy-, (1β,11β,12α)-
CBNumber:
CB71327541
분자식:
C20H24O7
포뮬러 무게:
376.4
MOL 파일:
981-15-7.mol
MSDS 파일:
SDS

ailanthone 속성

녹는점
235-237 °C
끓는 점
641.0±55.0 °C(Predicted)
밀도
1.47
저장 조건
Sealed in dry,Store in freezer, under -20°C
용해도
DMSO:100.0(Max Conc. mg/mL);265.67(Max Conc. mM)
물리적 상태
결정성 고체
산도 계수 (pKa)
11.85±0.70(Predicted)
LogP
-0.760 (est)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
그림문자(GHS): GHS hazard pictograms
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H300 삼키면 치명적임 급성 독성 물질 - 경구 구분 1,2 위험 GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
예방조치문구:
NFPA 704
0
4 0

ailanthone C화학적 특성, 용도, 생산

개요

Ailanthone is a quassinoid that has been found in Ailanthus and has diverse biological activities. It is active against the P. falciparum strains HB-3 and Dd-2 in vitro (IC50s = 0.003 and 0.037 μg/ml, respectively). Ailanthone is phytotoxic, inhibiting radish seed germination by 88% when used at a concentration of 1 mM. It inhibits dihydrotestosterone-induced androgen receptor transcriptional activity (IC50 = 69 nM in a reporter assay), as well as the growth and colony formation of LNCaP and 22RV1 androgen receptor-expressing cells, but not androgen receptor-negative PC3 and DU145 cells, when used at a concentration of 0.1 μM. Ailanthone (2 mg/kg) reduces tumor volume in 22Rv1, LNCaP, and VCaP castration-resistant prostate cancer (CRPC) mouse xenograft models.

ailanthone 준비 용품 및 원자재

원자재

준비 용품


ailanthone 공급 업체

글로벌( 136)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3620 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897
sales@biopurify.com China 3424 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28180 58
Shaanxi Pioneer Biotech Co., Ltd .
+8613259417953
sales@pioneerbiotech.com China 3000 58
Hubei xin bonus chemical co. LTD
86-13657291602
linda@hubeijusheng.com CHINA 22968 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873
sales@chemdad.com China 39916 58
career henan chemical co
+86-0371-86658258 15093356674;
factory@coreychem.com China 29826 58
Neostar United (Changzhou) Industrial Co., Ltd.
+86-519-519-85557386
marketing1@neostarunited.com China 8349 58
Wuhan ChemNorm Biotech Co.,Ltd.
+86-27-8439 4403 18971486879
sales@chemnorm.com CHINA 2935 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671
sales@tnjchem.com China 34572 58

ailanthone 관련 검색:

Copyright 2019 © ChemicalBook. All rights reserved