2-Amino-5-bromobenzoic acid
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2-Amino-5-bromobenzoic acid 속성
- 녹는점
- 213-215 °C (lit.)
- 끓는 점
- 265.51°C (rough estimate)
- 밀도
- 1.6841 (rough estimate)
- 굴절률
- 1.6120 (estimate)
- 저장 조건
- Keep in dark place,Inert atmosphere,Room temperature
- 용해도
- 메탄올과 디메틸설폭사이드에 용해됩니다.
- 산도 계수 (pKa)
- 4.55±0.10(Predicted)
- 물리적 상태
- 가루
- 색상
- 베이지색
- 감도
- Light Sensitive
- Merck
- 14,1405
- BRN
- 639028
- InChI
- InChI=1S/C7H6BrNO2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3H,9H2,(H,10,11)
- InChIKey
- CUKXRHLWPSBCTI-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C1=CC(Br)=CC=C1N
- CAS 데이터베이스
- 5794-88-7(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 22-36/37 | ||
| 안전지침서 | 26-38-36/37 | ||
| 유엔번호(UN No.) | UN 2811 6.1/PG 3 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | CB2557670 | ||
| 위험 참고 사항 | Harmful | ||
| 포장분류 | 6.1/PG 3 | ||
| HS 번호 | 29224999 |
2-Amino-5-bromobenzoic acid C화학적 특성, 용도, 생산
화학적 성질
slight yellow to white powder물리적 성질
2-Amino-5-bromobenzoic acid has 17 atoms, meaning 45 vibrational modes in three main parts: Carboxyl group, amine group, and benzene. The molecule's most mechanically active parts are the carboxyl and amine groups. They exhibit rocking, swinging, and every kind of mechanical motion beside H immigrations between each other. For this reason, the molecule is not a simple carboxylic acid nor a primary amine[1].용도
2-Amino-5-bromobenzoic acid is a brominated derivative of Antharilinic Acid (A679222). 2-Amino-5-bromobenzoic acid displays plant growth-regulator activity. 2-Amino-5-bromobenzoic acid is used in the preparation of hepatitis C virus NS5b RNA polymerase inhibitors.제조 방법
2-Amino-5-bromobenzoic acid is synthesized from o-aminobenzoic acid by bromination.Synthesis of 2-amino-5-bromobenzoic acid (4c, CAS: 5794-88-7) and 2-amino3,5-dibromobenzoic acid (4d, CAS: 609-85-8): A solution of bromine (7.2 g, 2 mL, 40 mmol) in 47 mL glacial acetic acid was added dropwise to sodium 2-aminobenzoate (6.4 g, 40 mmol) in 32 mL of glacial acetic acid at 15 °С and the mixture was stirred for 1 h at the same temperature. The product was filtered off, washed with benzene and dried in the dark. The bromobenzoic acids containing mixture (0.5 g) was added to 10 mL of boiling water followed by the addition of 1.3 mL of concentrated hydrochloric acid and hot filtration under vacuum. The insoluble material contained 2-amino-3,5-dibromobenzoic acid, whereas 2- amino-5-bromobenzoic acid precipitated upon cooling of the filtrate.
2-Amino-5-bromobenzoic acid (4c) IR (suspension in nujol, cm?1 ): 3497, 3383, 1675, 1616, 1587, 1548, 1423, 1377, 1316, 1292, 1239, 1160, 1127, 812, 748, 691.
2-Amino-5-bromobenzoic acid 준비 용품 및 원자재
원자재
안트라닐산
C.I.Vat Blue 35
6-Bromo-2-methyl-4H-3,1-benzoxazin-4-one
나트륨 안트라
2-ACETAMIDO-5-BROMOBENZOIC ACID
4'-BROMO-2'-METHYLACETANILIDE
5-BROMO-2-NITRO-BENZOIC ACID
2-Amino-3,5-dibromobenzoic acid
METHYL 2-AMINO-5-BROMOBENZOATE
N-Acetylanthranilic acid
5-Bromoisatin
준비 용품
2-Amino-5-bromobenzoic acid 공급 업체
글로벌( 541)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Changzhou Jiuwu Chemical co., Ltd. | +86-0519-85121086 +8613775162768 |
info@jiuwuchem.cn | China | 75 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
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| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
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| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15928 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
| Anqing Chico Pharmaceutical Co., Ltd. | 15380796838 |
chloewu@chicopharm.cn | CHINA | 341 | 58 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Shanghai Arbor Chemical Co., Ltd. | 021-60451682 |
act@arborchemical.com | CHINA | 906 | 58 |