2-IMINOBIOTIN HYDROBROMIDE

2-IMINOBIOTIN HYDROBROMIDE 구조식 이미지
카스 번호:
13395-35-2
상품명:
2-IMINOBIOTIN HYDROBROMIDE
동의어(영문):
2-IMINOBIOTIN;Iminobiotin;2-Iminobiotine;GUANIDINOBIOTIN;2-IMINOBIOTIN 98+%;2- Iminobiotin 13395-35-2;2-Iminobiotin >=98% (TLC);2-IMINOBIOTIN HYDROBROMIDE;Tetrahydro-2-iminothieno[3,4-d]imidazoline-4-valeric acid;HEXAHYDRO-2-IMINO-1H-THIENO[3,4-D]IMIDAZOLE-4-PENTANOIC ACID
CBNumber:
CB7157057
분자식:
C10H17N3O2S
포뮬러 무게:
243.33
MOL 파일:
13395-35-2.mol
MSDS 파일:
SDS

2-IMINOBIOTIN HYDROBROMIDE 속성

끓는 점
477.3±55.0 °C(Predicted)
밀도
1.60
저장 조건
2-8°C
용해도
1M HCl: 50mg/mL, 투명, 무색
물리적 상태
백색 내지 회백색 분말.
산도 계수 (pKa)
4.73±0.10(Predicted)
BRN
18952

안전

안전지침서 22-24/25
WGK 독일 3
F 고인화성물질 10-21

2-IMINOBIOTIN HYDROBROMIDE C화학적 특성, 용도, 생산

용도

2-Iminobiotin has been used as a competitive inhibitor to bind to biotic binding sites on streptavidin in order to restore fluorescence signal.

일반 설명

2-Iminobiotin is a cyclic guanidino analog of biotin that has high affinity for avidin at high pH (>9) and low affinity at low pH (<6). The proteins that are iminobiotinylated are selectively contained within the avidin column at pH 9 to 11 and may be eluted at pH 4 or by the addition of biotin. This technique may be very useful in the study of cell surface proteins by labeling and selectively recovering the components that are periodate-sensitive from intact human erythrocyte surface. 2-Iminobiotin reversibly inhibits NOS (nitric oxide synthases) via its guanidino group. It inhibits NO biosynthesis and may be important to understand the binding-site interactions for this important class of enzymes. NOS oxidizes the guanidino-nitrogen of L-arginine to produce nitric oxide and L-citrulline.

2-IMINOBIOTIN HYDROBROMIDE 준비 용품 및 원자재

원자재

준비 용품


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