2'-Deoxyadenosine
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2'-Deoxyadenosine 속성
- 녹는점
- 187-189 °C
- 끓는 점
- 394.4°C (rough estimate)
- 밀도
- 1.2938 (rough estimate)
- 굴절률
- 1.7610 (estimate)
- 저장 조건
- Keep in dark place,Inert atmosphere,2-8°C
- 용해도
- DMSO(약간 용해됨), 메탄올(약간 용해됨), 물(약간 용해됨)
- 산도 계수 (pKa)
- pK1:3.8(+1) (25°C,μ=0.1)
- 물리적 상태
- 가루
- 색상
- 하얀색
- 수소이온지수(pH)
- 3.8
- 수용성
- 물과 가성소다에 용해됩니다.
- 최대 파장(λmax)
- 258 (pH 2);260 (pH 7)
- 안정성
- 흡습성
- InChI
- InChI=1S/C10H13N5O3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7/h3-7,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,7+/m0/s1
- InChIKey
- OLXZPDWKRNYJJZ-RRKCRQDMSA-N
- SMILES
- OC[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N)N=C2)C[C@@H]1O
- CAS 데이터베이스
- 958-09-8(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
유엔번호(UN No.) | 2811 | ||
---|---|---|---|
WGK 독일 | 3 | ||
RTECS 번호 | AU7358600 | ||
F 고인화성물질 | 10-23 | ||
TSCA | Yes | ||
위험 등급 | 6.1 | ||
포장분류 | Ⅲ | ||
HS 번호 | 2934999090 |
2'-Deoxyadenosine C화학적 특성, 용도, 생산
개요
2'-Deoxyadenosine is a natural deoxyribonucleoside, which is a structural fragment of deoxyribonucleic acid DNA. It is a purine nucleoside component of DNA comprised of adenosine linked by its N9 nitrogen to the C1 carbon of deoxyribose. Like other natural nucleosides, it is involved in the transmission of genetic information in almost all biological cells, affecting protein synthesis and polysaccharide. It plays a very important role in regulating the growth, proliferation, differentiation and inhibition of cells in vivo.용도
2'-Deoxyadenosine is used in paradoxical stimulation study of human sperm motility. It plays an essential role as sperm motility stimulants used in sperm micro-injection on mouse and human embryo development. It finds an application in some cells as an energy source under energy stress conditions. It is involved in various biological processes to compare the functions of adenosine analogues.정의
ChEBI: 2'-deoxyadenosine is a purine 2'-deoxyribonucleoside having adenine as the nucleobase. It has a role as a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a purines 2'-deoxy-D-ribonucleoside and a purine 2'-deoxyribonucleoside.제조 방법
2'-deoxyadenosine synthesis: esterification of adenosine, acylation of an acylating agent and an acid binding agent to obtain an acylate; the obtained acylate is then subjected to reduction and purification to obtain 2'-deoxyadenosine. The esterification agent used in the esterification process is dialkyl tin oxide, 2'-O-p-toluenesulfonyladenosine is synthesized from adenosine, and 2'-deoxyadenosine is synthesized from 2'-O-p-toluenesulfonyladenosine glycosides.생물학적 활성
2'-Deoxyadenosine is a deoxyribonucleoside and an intermediate in the purine nucleotide degradation pathway. It is transported into cells via facilitated diffusion or formed within cells by degradation of S-adenosylhomocysteine or AMP and is removed from cells by purine metabolism or is converted into adenine nucleotides. 2'-Deoxyadenosine has been used in the characterization of DNA conformations and the synthesis of nucleoside analogs as antiviral agents.Source
2'-Deoxyadenosine is a metabolite found in or produced by Escherichia coli (strain K12, MG1655). 2'-Deoxyadenosine is a natural product found in Streptomyces jiujiangensis, Fritillaria przewalskii, and other organisms with data available.2'-Deoxyadenosine 준비 용품 및 원자재
원자재
준비 용품
2'-Deoxyadenosine 공급 업체
글로벌( 412)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Wuhu Nuowei chemistry Co., Ltd. | +86-0553-2911116-802 +undefined17756524438 |
sales1@nuowei-chem.com | China | 1640 | 58 |
Yunbio Tech Co.,Ltd. | +86-010-60605551 +86-18046518538 |
yunbiochem@126.com | China | 321 | 58 |
SHANGHAI NOVRIBO BIOTECH | 17821030819 |
June.Liu@Desano.com | China | 73 | 58 |
Hangzhou Measure Life Technology Co., LTD | +8613343730176 |
2924244016@qq.com | China | 83 | 58 |
Allbiosyn Biotechnology Co.,Ltd. | +8618666985712 |
info@allbiosyn.com | China | 286 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12446 | 58 |
HangZhou RunYan Pharma Technology Co.,LTD. | +8618882027439 |
sales2@runyanpharma.com | China | 304 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21666 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32836 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29888 | 58 |
2'-Deoxyadenosine 관련 검색:
아데노신 삼인산 Na염 아데노신 트라이포스파타아제 3′,5′-사이클릭아데닐산 N6-벤조일-5'-O-(4,4'-디메톡시트리틸)-2'-탈산아데노신 2'-데옥시아데노신-5'-트리인산염, 디나트륨 염, 트리수화물 클라드리빈 코디체핀
Vidarabine
Deoxycholic acid
5'-Deoxyadenosylcobalamin
2'-Deoxyadenosine 5'-phosphate
Dideoxyadenosine
ADP
2'-Deoxyadenosine-5'-triphosphate, trisodiuM salt
c-di-AMP
ADENOSINE-2':3'-CYCLIC MONOPHOSPHATE, SODIUM SALT
[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-oxolan-2-yl]methoxyphosphonic acid
2'-O-Methyladenosine