N-Benzoylaminopurine
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N-Benzoylaminopurine 속성
- 녹는점
- 242-244°C
- 밀도
- 1.494 g/cm3
- 저장 조건
- 2-8°C
- 수용성
- 물에 불용성
- 용해도
- DMSO(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- powder to crystal
- 산도 계수 (pKa)
- 11.98±0.20(Predicted)
- 색상
- 흰색에서 거의 흰색
- BRN
- 20585
- InChI
- InChI=1S/C12H9N5O/c18-12(8-4-2-1-3-5-8)17-11-9-10(14-6-13-9)15-7-16-11/h1-7H,(H2,13,14,15,16,17,18)
- InChIKey
- QQJXZVKXNSFHRI-UHFFFAOYSA-N
- SMILES
- C(NC1=C2C(=NC=N1)NC=N2)(=O)C1=CC=CC=C1
- CAS 데이터베이스
- 4005-49-6(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
N-Benzoylaminopurine C화학적 특성, 용도, 생산
화학적 성질
White solidBiochem/physiol Actions
N6-Benzoyladenine comprises of adenine moiety and is a potent inhibitor of bromodomain-containing protein 4 (BRD4). N6-Benzoyladenine modulates tumor necrosis factor α (TNF-α) levels. It elicits cytotoxicity in liver and ileum cancer cells and may serve as a potential candidate agent for cancer chemotherapy.Synthesis
Benzoyl chloride (1.3 mL, 11 mmol) was added dropwise over 30 min to a stirred suspension of adenine (1.35 g, 10 mmol) in dry pyridine, and stirring was continued at 100 °C for a further 3 h, and the reaction mixture was allowed to stand overnight at room temperature. The reaction was quenched with methanol and the solvents were removed under reduced pressure. The residue was triturated in hot isopropanol and dried in vacuo to give 8 as a white solid: yield 2.15 g (90%). MS (+ESI): m/z 240 [M+H]+; 1H NMR (400 MHz, d-DMSO): δ11.50 (s, 1H), 8.74 (s, 1H), 8.52 (s, 1H), 8.11 (d, 2H, J = 7.2 Hz), 7.66 (t, 1H, J = 7.2 Hz), 7.58 (t, 2H, J = 7.2 Hz).
N-Benzoylaminopurine 준비 용품 및 원자재
원자재
Benzamide, N-[9-(3-C-ethenyl-β-D-xylofuranosyl)-9H-purin-6-yl]-
Benzamide, N-[9-[3-C-ethenyl-3,5-O-(1-methylethylidene)-β-D-xylofuranosyl]-9H-purin-6-yl]-
Adenosine, 2',5'-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-
벤조산
염화벤조일
준비 용품
N-Benzoylaminopurine 공급 업체
글로벌( 255)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hangzhou Measure Life Technology Co., LTD | +8613343730176 |
2924244016@qq.com | China | 83 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 7845 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Shanghai Arbor Chemical Co., Ltd. | 021-60451682 |
act@arborchemical.com | CHINA | 906 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 |
sales@sdzschem.com | China | 2931 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 |
figo.gao@foxmail.com | China | 6992 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 |
sales@finerchem.com | China | 2967 | 58 |
N-Benzoylaminopurine 관련 검색:
아데닌 벤즈아마이드 N6-벤조일-5'-O-(4,4'-디메톡시트리틸)-2'-탈산아데노신
Chlorantraniliprole
Adenine Sulfate
Adenine phosphate salt（1：1）
N6-Benzoyl-2'-deoxyadenosine
DMT-2'O-TBDMS-rA(bz) Phosphoramidite
DMT-dA(bz) Phosphoramidite
5'-O-(4,4'-DIMETHOXYTRITYL)-N6-BENZOYL-2'-DEOXYADENOSINE-3'-O-SUCCINIC ACID
3'-DA CEP
N-BENZOYLADENOSINE
N6,3'-O-DIBENZOYL-2'-DEOXYADENOSINE
N6-ANISOYLADENOSINE
N-Benzoylaminopurine
AURORA 5003
5'DIMETHOXYTRITYL DA(BZ)+DG(IBU)+DC(BZ)+T BETA-CYANOETHYL PHOSPHORAMIDITE
BZ-DMT-DEOXYADENOSINE 2-CLPH DIESTER TRIETHYLAMMONIUM SALT