Dyphylline is the N-7 dihydroxypropyl derivative of theophylline and is not a theophylline salt.
Dyphylline does not get metabolized to theophylline in vivo, and even though it contains 70%
theophylline by molecular weight ratio, the equivalent amount to theophylline is not known.
Dosing must be accomplished independently by monitoring dyphylline blood levels. Dyphylline
has a diminished bronchodilator effect compared to theophylline, but it may have lower and less
serious side effects. Dosage forms available are an elixir and tablets.
화학적 성질
white to light yellow crystal powder
용도
PDE inhibitor, bronchodilator, vasodilator
정의
ChEBI: An oxopurine that is theophylline bearing a 2,3-dihydroxypropyl group at the 7 position. It has broncho- and vasodilator properties, and is used in the treatment of asthma, cardiac dyspnea, and bronchitis. It is also an ingredient in preparations that have
been promoted for coughs.
