진세노사이드-Rb1
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진세노사이드-Rb1 속성
- 녹는점
- 197.5°C
- 끓는 점
- 766.35°C (rough estimate)
- 밀도
- 1.0971 (rough estimate)
- 굴절률
- 1.6500 (estimate)
- 저장 조건
- 2-8°C
- 용해도
- 메탄올: 용해성9.80 - 10.20 mg/mL, 투명, 무색 ~ 희미한 노란색
- 산도 계수 (pKa)
- 12.85±0.70(Predicted)
- 물리적 상태
- Solid
- 색상
- 미색부터 페일 베이지까지
- 안정성
- 흡습성
- InChIKey
- GZYPWOGIYAIIPV-VOKNSFSUNA-N
- LogP
- 2.900 (est)
- CAS 데이터베이스
- 41753-43-9(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xn,Xi,T,F | ||
---|---|---|---|
위험 카페고리 넘버 | 20/21/22-39/23/24/25-23/24/25-11 | ||
안전지침서 | 26-36-45-36/37-16-7 | ||
WGK 독일 | 3 | ||
RTECS 번호 | LZ5856000 | ||
HS 번호 | 29389090 | ||
독성 | oms-rat-ipr 50 mg/kg CPBTAL 24,2400,76 |
진세노사이드-Rb1 C화학적 특성, 용도, 생산
개요
Ginsenoside Rb1, a glycosylated PPD type ginsenoside with two sugars linked to C-3 and two sugars linked to C-20, is the major active constituent of American ginseng. Studies have demonstrated the anti-aging effects of ginsenoside Rb1 at both animal and cell levels. 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol (20GPPD) is the major ingredient of ginsenoside Rb1, which has been shown to increase HAS2 expression by phosphorylating ERK and AKT signaling in human keratinocytes in a dose-dependent manner in vitro.용도
A major bioactive component of panax ginseng that promotes neurotransmitter release by modulating phosphorylation of synapsins through a cAMP-dependent protein kinase pathway. It has been reported to display immunostimulatory and anticancer effects.정의
ChEBI: Ginsenoside Rb1 is a ginsenoside found in Panax ginseng and Panax japonicus var. major that is ginsenoside Rd in which the beta-D-glucopyranoside group at position 20 is replaced by a beta-D-glucopyranosyl-beta-D-glucopyranoside group. It has a role as a neuroprotective agent, an anti-obesity agent, an anti-inflammatory drug, an apoptosis inhibitor, a radical scavenger and a plant metabolite. It is a ginsenoside, a glycoside and a tetracyclic triterpenoid. It is functionally related to a ginsenoside Rd.benefits
Ginsenoside Rb1 (G-Rb1) is a tetracyclic triterpenoid mainly obtained from the roots or stems of Panax notoginseng and ginseng by extraction and purification. It is one of the main bioactive compounds of ginseng with minimal toxicity and neurotrophic and neuroprotective effects on brain injury. G-Rb1 promotes hippocampal nerve regeneration, enhances learning and memory, and has anti-aging and anti-fatigue effects. In addition, it activates antioxidants, stimulates the immune system, has anti-apoptotic activity, and maintains cell adenosine triphosphate (ATP) levels[1].일반 설명
Ginsenoside Rb1 (Gypenoside Ⅲ) is a protopanaxadiol that has diverse in vitro and in vivo effects, including neuroprotective, anti-inflammatory, and anti-obesity actions. Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits Na+, K+-ATPase activity with IC50 of 6.3±1.0 μM. Ginsenoside also inhibits IRAK-1 activation and phosphorylation of NF-κB p65. Ginsenoside Rb1 reduces the expressions of TLR3, TLR4 and TRAF-6, and down-regulates the levels of TNF-α, IFN-β and iNOS.Safety Profile
Poison by intravenous route. Moderately toxic by intraperitoneal route. Mutation data reported. Whenheated to decomposition it emits acrid smoke and irritating fumes.진세노사이드-Rb1 준비 용품 및 원자재
원자재
준비 용품
진세노사이드-Rb1 공급 업체
글로벌( 389)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +86-18791163155 +86-13119157289 |
13119157289@163.com | China | 2972 | 58 |
Xi'an ZB Biotech Co.,Ltd | +8618591943808 |
sales01@xazbbio.com | China | 816 | 58 |
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +8618829768577 |
gao490372054@gamil.com | China | 1250 | 58 |
Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 |
qinhe02@xaltbio.com | China | 1000 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 20292 | 58 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 18628 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21667 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9308 | 55 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 |
sales@fine-chemtech.com | CHINA | 885 | 55 |
진세노사이드-Rb1 관련 검색:
진세노사이드알이 진세노사이드알디 사포닌 진세노사이드-Rb1
TRIBULOSIDE
GINSENOSIDE RE
Ginsenoside Rg1
Ginsenoside Rh2
GinsenosideRo
20(R)-Ginsenoside Rg3
Ginsenoside Rg2
Ginsenoside Rb3 (CAS#68403-26-8),GINSENOSIDE RB3
GINSENOSIDE RB2,GINSENOSIDE Rb2 hplc,GINSENOSIDE RB2 WITH HPLC
Panaxadiol
Panaxatriol
Ginsenoside Rg3
Ginsenoside-Rg5
Ginsenoside Rh1