KIGAMICIN C

KIGAMICIN C 구조식 이미지
카스 번호:
680571-51-1
상품명:
KIGAMICIN C
동의어(영문):
KIGAMICIN C;Oxazolo[3,2-b]xantheno[4',3',2':4,5][1,3]benzodioxino[7,6-g]isoquinoline-16,19-dione, 3-[[(2S,5S,6R)-5-[(2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl)oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-1,2,3,4,8a,9,11,11a,13,14-decahydro-1,4,17,18-tetrahydroxy-11a-methyl-, (1S,3R,4S,8aR,11aR)-
CBNumber:
CB72453298
분자식:
C41H47NO16
포뮬러 무게:
809.81
MOL 파일:
680571-51-1.mol

KIGAMICIN C 속성

저장 조건
Store at -20°C
용해도
DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
물리적 상태
노란색 가루.

안전

KIGAMICIN C C화학적 특성, 용도, 생산

용도

Kigamicin C was discovered by an anti-austerity strategy, targeting cancer cells' tolerance to starvation. It selectively kills PANC-1 cells (a pancreatic cell line) at concentrations 100 times lower under nutrient starved conditions than in normal conditions. The mechanism of action is proposed to be via blockade of aPKB/Akt activation, caused by the withdrawal of nutrients. It is active in vivo against a human pancreatic cancer xenograft model. Kigamicin C also inhibits the growth of Gram positive bacteria including MRSA, but is not active against Gram negative bacteria.

KIGAMICIN C 준비 용품 및 원자재

원자재

준비 용품


KIGAMICIN C 공급 업체

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