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MK-2206 2HCl

MK-2206 2HCl 구조식 이미지
카스 번호:
1032350-13-2
상품명:
MK-2206 2HCl
동의어(영문):
MK-2206;MK-2206 2HCl;MK-2206 HCl salt;MK 2206 (hydrochloride);MK-2206 Dihydrochloride;MK-2206 dihydrochloride, >=98%;MK 2206 dihydrochloride, 98%, an allosteric Akt inhibitor;8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one;8-[4-(1-AMINOCYCLOBUTYL)PHENYL]-9-PHENYL-1,2,4-TRIAZOLO[3,4-F][1,6]NAPHTHYRIDIN-3(2H)-ONE 2HCL;8-[4-(1-AMinocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one Hydrochloride
CBNumber:
CB72489901
분자식:
C25H21N5O
포뮬러 무게:
407.46714
MOL 파일:
1032350-13-2.mol

MK-2206 2HCl 속성

물리적 상태
Yellow powder.

안전

MK-2206 2HCl C화학적 특성, 용도, 생산

용도

A highly selective inhibitor of Akt. Akt1, IC50=8 nM; Akt2, IC50=12 nM; Akt3, IC50=65 nM.

용도

AZD 6244 and MK 2206 are targeted small-molecule drugs that inhibit MEK and AKT responses. The combination of AZD6244 and MK2206 has a significant synergistic effect on tumor growth in vitro and in vi vo and leads to increased survival rates in mice bearing highly aggressive human lung tumors. Antitumor agents.

MK-2206 2HCl 준비 용품 및 원자재

원자재

준비 용품


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