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Nintedanib

Nintedanib 구조식 이미지
카스 번호:
656247-17-5
상품명:
Nintedanib
동의어(영문):
100837;Nidanib;NTEDANIB;Vargatef;Intedanib;Nintedanib;INTEDANIB BASE;Nintedanib-016;Nintedanib whatsapp;Intedanib Vargatef
CBNumber:
CB72510401
분자식:
C31H33N5O4
포뮬러 무게:
539.64
MOL 파일:
656247-17-5.mol

Nintedanib 속성

끓는 점
742.2±60.0 °C(Predicted)
밀도
1.284±0.06 g/cm3(Predicted)
산도 계수 (pKa)
11.06±0.20(Predicted)
물리적 상태
Yellow solid.

안전

유해 물질 데이터 656247-17-5(Hazardous Substances Data)

Nintedanib C화학적 특성, 용도, 생산

용도

It is an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases; an indolinone as triple angiokinase inhibitors.

용도

BIBF1120 (Vargatef) is a potent inhibitor of VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively.

정의

ChEBI: A member of the class of oxindoles that is a kinase inhibitor used (in the form of its ethylsulfonate salt) for the treatment of idiopathic pulmonary fibrosis and cancer.

Nintedanib 준비 용품 및 원자재

원자재

준비 용품


Nintedanib 공급 업체

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