HE3235

HE3235 구조식 이미지
카스 번호:
183387-50-0
상품명:
HE3235
동의어(영문):
HE3235;Apoptone;Pregn-20-yne-3,17-diol, (3α,5α,17α)-;(3R,5S,8R,9S,10S,13S,14S,17R)-17-ethynyl-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthrene-3,17-diol
CBNumber:
CB72627947
분자식:
C21H32O2
포뮬러 무게:
316.49
MOL 파일:
183387-50-0.mol

HE3235 속성

끓는 점
430.1±18.0 °C(Predicted)
밀도
1.11±0.1 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
≤10mg/ml in ethanol;10mg/ml in DMSO;10mg/ml in dimethyl formamide
물리적 상태
결정질 고체
산도 계수 (pKa)
13.11±0.70(Predicted)

안전

HE3235 C화학적 특성, 용도, 생산

개요

HE-3235 is a synthetic adrenal hormone, an androstanediol analog, that acts as an androgen receptor antagonist. In an androgen receptor-dependent manner, it downregulates anti-apoptotic genes, while increasing the expression of pro-apoptotic genes, thus stimulating apoptosis. HE-3235 has been shown to inhibit androstenediol-dependent LNCaP cell tumor growth both in vitro (IC50 = 6 nM) and in xenograft models in vivo.

HE3235 준비 용품 및 원자재

원자재

준비 용품


HE3235 공급 업체

글로벌( 17)공급 업체
공급자 전화 이메일 국가 제품 수 이점
NCE Biomedical Co.,Ltd. 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
China 1494 55
SPIRO PHARMA
eric_feng1954@126.com China 9254 55
MedBioPharmaceutical Technology Inc 021-69568360 18916172912
order@med-bio.cn China 8141 58
Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369
3477467573@qq.com China 8618 58
TargetMol Chemicals Inc. 4008200310
marketing@tsbiochem.com China 24024 58
Suzhou Meishi Biotechnology Co., Ltd. 1173954148q
meishipharma@126.com China 20035 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
customer_service@efebio.com China 8740 58
ApexBio Technology --
sales@apexbt.com United States 6254 58

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