코직산
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코직산 속성
- 녹는점
- 152-155 °C (lit.)
- 끓는 점
- 179.65°C (rough estimate)
- 밀도
- 1.1712 (rough estimate)
- 굴절률
- 1.4434 (estimate)
- 저장 조건
- Store below +30°C.
- 용해도
- DMSO(약간 용해됨), 메탄올(약간 용해됨, 초음파처리)
- 물리적 상태
- 결정성 분말
- 산도 계수 (pKa)
- 7.9(at 25℃)
- 색상
- 흰색에서 베이지색 갈색
- 수용성
- 녹는
- 최대 파장(λmax)
- 269nm(CHCl3)(lit.)
- Merck
- 14,5317
- BRN
- 120895
- 안정성
- 안정적인. 타기 쉬운. 강한 산화제와 호환되지 않습니다.
- LogP
- -0.640
- CAS 데이터베이스
- 501-30-4(CAS DataBase Reference)
- IARC
- 3 (Vol. 79) 2001
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 40-68 | ||
| 안전지침서 | 22-24/25-36/37-36 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | UQ0875000 | ||
| HS 번호 | 29329995 | ||
| 유해 물질 데이터 | 501-30-4(Hazardous Substances Data) | ||
| 기존화학 물질 | 2014-3-5741 |
코직산 C화학적 특성, 용도, 생산
화학적 성질
tan powder용도
kojic acid is a skin-lightening agent that acts through anti-oxidant activity. Kojic acid is a tyrosinase inhibitor, although it is not as effective as licorice extract. When combined with allantoin and other proper ingredients in sunscreen preparations, the mixture can inhibit uV-caused erythema and accelerate wound healing. It is also found to be skin sensitizing and can be irritating.정의
ChEBI: A pyranone that is 4H-pyran substituted by a hydroxy group at position 5, a hydroxymethyl group at position 2 and an oxo group at position 4. It has been isolated from the fungus Aspergillus oryzae.일반 설명
Kojic acid, a tyrosinase inhibitor, is produced by several fungi species, including Aspergillus oryzae. It exhibits skin-lightening property, due to its ability to chelate the copper-containing enzyme tyrosinase in the formation of melanin. Kojic acid is also commonly used as a whitening agent in regular cosmetics, bleaching cosmetics, etc. It is found to be a therapeutic agent and helps in preventing pigmentation.Purification Methods
Crystallise the acid from MeOH (charcoal) by adding Et2O. It sublimes at 150-200o/0.1torr. [Beilstein 18 II 57, 18 III/IV 1145, 18/2 V 516.]코직산 준비 용품 및 원자재
원자재
준비 용품
말톨
에틸하이드록시피론
5-(benzyloxy)-4-oxo-4H-pyran-2-carboxylic acid
4H-Pyran-4-one,3-methoxy-(6CI,7CI,8CI,9CI)
2-amino-4-(2-fluorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carbonitrile
3-(benzyloxy)-1,4-dihydropyridin-4-one
4-Thiazoleacetic acid, α-[[[1,5-bis(diphenylmethoxy)-1,4-dihydro-4-oxo-2-pyridinyl]methoxy]imino]-2-[(triphenylmethyl)amino]-, (αZ)-
2,3-DIHYDRO[1,4]DIOXINO[2,3-C]PYRIDINE-7-CARBALDEHYDE
WS 75624 B
코직산 공급 업체
글로벌( 693)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Dangtong Import and export Co LTD | +8615632927689 |
admin@hbdangtong.com | China | 991 | 58 |
| Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 |
gksales1@gk-bio.com | China | 9339 | 58 |
| Shandong Zhishang New Material Co., Ltd. | +8617653113209 |
sales002@sdzschem.com | China | 3050 | 58 |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 |
qinhe02@xaltbio.com | China | 1000 | 58 |
| Chongqing Zhihe Biopharmaceutical Co., Ltd. | +86-18580541567 +86-17782035140 |
sales@zhswyy.com | China | 338 | 58 |
| Shanghai Affida new material science and technology center | +undefined15081010295 |
2691956269@qq.com | China | 359 | 58 |
| XI'AN TIANGUANGYUAN BIOTECH CO., LTD. | +86-029-86333380 18829239519 |
sales06@tgybio.com | China | 961 | 58 |
| Henan Tengmao Chemical Technology Co. LTD | +8615238638457 |
salesvip2@hntmhg.com | China | 415 | 58 |
| Hangzhou ICH Biofarm Co., Ltd | +undefined8613073685410 |
sales@ichemie.com | China | 985 | 58 |
| Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 |
xinshengkeji@xsmaterial.com | China | 1100 | 58 |
코직산 관련 검색:
트리스(하이드록시메틸)아미노메탄 나트륨 카르복시메틸 셀룰로스 시트르산 아세트산 엽산 트리메틸롤프로판 코직산
Hyaluronic acid
Tetrahydro-4H-pyran-4-one
CHLOROPHOSPHONAZO III
methylol cellulose
Ascoric Acid
CETRAXATE, HYDROCHLORIDE
Kojic acid dipalmitate
5-hydroxy-4-oxo-4H-pyran-2-carboxylic acid
KOJIC ACID SODIUM SALT HYDRATE
CETRAXATE, HYDROCHLORIDE
4H-PYRAN-4-ONE