hbf386;sanamycin;sanamicia;nsc-18268;CACTINOMYCIN;ACTINOMYCIN C;actinochrysin;Actinochrysin C;ACTINOMYCIN C USP/EP/BP;ACTINOMYCIN C FROM STREPTOMYCES &
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P320
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P321
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P322
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P330
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P361
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P363
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P403+P233
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P405
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P501
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ACTINOMYCIN C C화학적 특성, 용도, 생산
용도
Actinomycin C is an antibiotic produced by?Streptomyces chrysomallus that intercalates DNA.
Purification Methods
(A commercial mixture of Actinomycin C1 5%, C2 30% and C3 65% is available). Actinomycin C1 (native) crystallises from EtOAc as red crystals, is soluble in CHCl3, *C6H6 and Me2CO, and has m 246-247o(dec), [] 20D -328o (0.22, MeOH) and max 443nm ( 25,000) and 240nm ( 34,000). Actinomycin C2 (native) crystallises as red needles from EtOAc and has m 244-246o(dec), [] D -325o (c 0.2, MeOH), max 443nm ( 25,300) and 240nm ( 33,400). Actinomycin C3 (native) recrystallises from cyclohexane, or *C6H6/MeOH/cyclohexane as red needles with m 238-241o (dec), [] D -321o (c 0.2, MeOH), max 443nm ( 25,000) and 240nm ( 33,300). [Brockman & Lackner, Chem Ber 101 1312 1968.] Itis light sensitive.[Beilstein 27 III/IV 9642.]
