CeftazidiMe

CeftazidiMe 구조식 이미지
카스 번호:
72558-82-8
상품명:
CeftazidiMe
동의어(영문):
hy;CEFTAZIDINE;CeftazidiMe with SodiuM Carbonate;Tazidime;Ceptaz;Fortaz;Ceftazidime CRS;caz;sn401;C06889
CBNumber:
CB7289569
분자식:
C22H22N6O7S2
포뮬러 무게:
546.57
MOL 파일:
72558-82-8.mol

CeftazidiMe 속성

저장 조건
under inert gas (nitrogen or Argon) at 2–8 °C
용해도
≥21.25 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
물리적 상태
powder to crystal
색상
White to Orange to Green
Merck
14,1946
안정성
안정적이지만 냉장 보관하세요. 강한 산화제, 질산, 과망간산염, 과산화물과 호환되지 않습니다.
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xn
위험 카페고리 넘버 20/21/22-36/37/38
안전지침서 26-36
RTECS 번호 UU2225000
HS 번호 29419000
그림문자(GHS): GHS hazard pictograms
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H317 알레르기성 피부 반응을 일으킬 수 있음 피부 과민성 물질 구분 1 경고 GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H334 흡입 시 알레르기성 반응, 천식 또는 호흡 곤란 등을 일으킬 수 있음 호흡기 과민성 물질 구분 1 위험 GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P272 작업장 밖으로 오염된 의복을 반출하지 마시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P284 호흡 보호구를 착용하시오.
P501 ...에 내용물 / 용기를 폐기 하시오.
NFPA 704
0
1 0

CeftazidiMe C화학적 특성, 용도, 생산

개요

In ceftazidime the oxime moiety is more complex, containing two methyl groups and a carboxylic acid. This assemblage conveys even more pronounced β-lactamase stability, greater anti–Pseudomonas aerugi nosa, and increased activity against Gram-positive organisms. The C-3 side chain has been replaced by a charged pyridinium moiety. The latter considerably enhances water solubility and also highly activates the β-lactam bond toward cleavage. The drug must be protected against heat and light and may darken without significant loss of potency. It is not stable under some conditions. such as the presence of aminoglycosides and vancomycin. It also is attacked readily in sodium bicarbonate solutions. Resistance is mediated by chromosomally mediated β-lactamases and by lack of penetration into target bacteria. Otherwise, it has a very broad antibacterial spectrum.

화학적 성질

solid

용도

Like most of the third-generation cephalosporin antibiotics described above, ceftazidime has a broad spectrum of antimicrobial action, including the most clinically important microorganisms: Gram-positive, Gram-negative, aerobic, and anaerobic. It is resistant to most beta-lactamases of Gram-positive and Gram-negative bacteria. It is used for treating most serious bacterial infections. Synonyms of this drug are fortum, ceftim, stacef, and tazicef.

정의

ChEBI: A cephalosporin bearing pyridinium-1-ylmethyl and {[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetamido groups at positions 3 and 7, respectively, of the cephem skeleton.

CeftazidiMe 준비 용품 및 원자재

원자재

준비 용품


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