퀴놀린산
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퀴놀린산 속성
- 녹는점
- 188-190 °C (dec.) (lit.)
- 끓는 점
- 295.67°C (rough estimate)
- 밀도
- 1.5216 (rough estimate)
- 굴절률
- 1.6280 (estimate)
- 저장 조건
- Keep in dark place,Sealed in dry,Room Temperature
- 용해도
- 10g/L
- 물리적 상태
- 결정성 분말
- 산도 계수 (pKa)
- 2.43(at 25℃)
- 색상
- 흰색에서 밝은 노란색-베이지색
- 냄새
- 냄새 없는
- 수용성
- 0.55g/100mL
- Merck
- 14,8073
- BRN
- 137110
- InChIKey
- GJAWHXHKYYXBSV-UHFFFAOYSA-N
- CAS 데이터베이스
- 89-00-9(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38-33 | ||
| 안전지침서 | 26-36/37-24/25-37 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | US7967250 | ||
| TSCA | T | ||
| 위험 등급 | IRRITANT | ||
| HS 번호 | 29333999 | ||
| 유해 물질 데이터 | 89-00-9(Hazardous Substances Data) | ||
| 독성 | Focal injection of quinolinic acid into specific areas of the brain produces neuronal damage although sparing axons of passage. Similarities between the biochemical and morphological profiles of these lesions and human neuropathy seen in neurodegenerative diseases have led to the proposal that endogenous excitotoxins may play a role in such neurodegenerative disease states. Quinolinic acid is an intermediate in the kynurenine pathway of tryptophan metabolism and has been detected in the brains of several mammals including man. The neuroexcitatory action is thought to be mediated via interaction with the N-methyl-D-aspartate (NMDA) receptor of the glutamate family. No mechanism for quinolinic acid removal, nor for synaptic inactivation, has been found, and consequently accumulation of concentrations capa_x0002_ble of inducing neuronal degeneration and death may occur. | ||
| 기존화학 물질 | KE-29939 |
퀴놀린산 C화학적 특성, 용도, 생산
화학적 성질
White powder;Light yellow powder용도
Quinolinic acid is an endogenous NMDA agonist. Quinolinic acid is a metabolite of tryptophan that acts as a putative NMDA receptor agonist. Quinolinic acid is an ?excitotoxic? metabolite and an agonist of N-methyl-D-aspartate receptors. properties of KYNA raise the possibility of a functional link between KYNA and QUIN in the brain which may be of relevance for an understanding of human neurodegenerative disorders. Quinolinic acid is a potent endogenous excitant at amino acid receptors in CNS.위험도
A poison by skin contact. Moderately toxic by ingestion. A mild skin irritant.공업 용도
The use of quinolinic acid during flotation of hematite results in the adsorption of quinoline on hematite, allowing amine to selectively adsorb onto the hematite surface.생물학적 활성
Endogenous NMDA agonist and transmitter candidate. May distinguish between NMDA receptor subtypes.Safety Profile
A poison by skin contact. Moderately toxic by ingestion. Experimental reproductive effects. A mdd skinn irritant. When heated to decomposition it emits toxic vapors of NOx.퀴놀린산 준비 용품 및 원자재
원자재
Diethyl oxalacetate
아크롤레인
퀴놀린
에틸알코올
Dicarboxylic Acid
과망간산칼륨
KZESTKDHUUMSOC-UHFFFAOYSA-N
2,3-Pyridinedicarboxylic acid copper(II) salt
Diethyl pyridine-2,3-dicarboxylate
5-BROMO-8-NITROQUINOLINE
3-히드록시안트라닐산
8-Quinolinesulfonyl chloride
8-하이드록시퀴놀린
6-Methylquinoline
8-Aminoquinoline
피콜린산
준비 용품
3-TERT-BUTOXYCARBONYLAMINO-PYRIDINE-2-CARBOXYLIC ACID
METHYL 3-CYANOPYRIDINE-2-CARBOXYLATE
3-Amino-2-pyridinecarboxylic acid
5-Methylpyridine-2,3-dicarboxylic acid
3-CARBAMOYLPICOLINIC ACID
3-AMINO-6-BROMO-PYRIDIN-2-OL
5-Methoxymethyl-2,3-pyridinedicarboxylic acid
5H-Pyrrolo[3,4-b]pyridine-5,7(6H)-dione
METHYL 3-(CHLOROCARBONYL)PYRIDINE-2-CARBOXYLATE HYDROCHLORIDE
3-CYANOPYRIDINE-2-CARBOXYLIC ACID
2-(AMINOCARBONYL)NICOTINIC ACID
3-(METHOXYCARBONYL)PYRIDINE-2-CARBOXYLIC ACID
퀴놀린산 공급 업체
글로벌( 565)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12453 | 58 |
| Hebei Guanlang Biotechnology Co,.LTD | +8619930503252 |
daisy@crovellbio.com | China | 5964 | 58 |
| shandong exelon biochem co.ld | +86-533-2119995 +8615053330977 |
451614802@QQ.com | China | 28 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 |
sales@frappschem.com | China | 885 | 50 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21695 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 |
info@tnjchem.com | China | 2989 | 55 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 |
admin@nexconn.com | China | 7838 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |