퀴놀린산

퀴놀린산
퀴놀린산 구조식 이미지
카스 번호:
89-00-9
한글명:
퀴놀린산
동의어(한글):
2,3-피리딘디카르복시산;퀴놀린산
상품명:
Quinolinic acid
동의어(영문):
PYRIDINE-2,3-DICARBOXYLIC ACID;2,3-PYRIDINEDICARBOXYLIC ACID;QUIN;2,3-Pyridinedicarboxylic;Pyridine-2,3-dicarboxylate;2,3-PyridinedicarboxylicAcid99%;109/KG;NSC 18836;NSC 13127;NSC 403247
CBNumber:
CB7316162
분자식:
C7H5NO4
포뮬러 무게:
167.12
MOL 파일:
89-00-9.mol
MSDS 파일:
SDS

퀴놀린산 속성

녹는점
188-190 °C (dec.) (lit.)
끓는 점
295.67°C (rough estimate)
밀도
1.5216 (rough estimate)
굴절률
1.6280 (estimate)
저장 조건
Keep in dark place,Sealed in dry,Room Temperature
용해도
10g/L
물리적 상태
결정성 분말
산도 계수 (pKa)
2.43(at 25℃)
색상
흰색에서 밝은 노란색-베이지색
냄새
냄새 없는
수용성
0.55g/100mL
Merck
14,8073
BRN
137110
InChIKey
GJAWHXHKYYXBSV-UHFFFAOYSA-N
CAS 데이터베이스
89-00-9(CAS DataBase Reference)
EPA
2,3-Pyridinedicarboxylic acid (89-00-9)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xi
위험 카페고리 넘버 36/37/38-33
안전지침서 26-36/37-24/25-37
WGK 독일 3
RTECS 번호 US7967250
TSCA T
위험 등급 IRRITANT
HS 번호 29333999
유해 물질 데이터 89-00-9(Hazardous Substances Data)
독성 Focal injection of quinolinic acid into specific areas of the brain produces neuronal damage although sparing axons of passage. Similarities between the biochemical and morphological profiles of these lesions and human neuropathy seen in neurodegenerative diseases have led to the proposal that endogenous excitotoxins may play a role in such neurodegenerative disease states. Quinolinic acid is an intermediate in the kynurenine pathway of tryptophan metabolism and has been detected in the brains of several mammals including man. The neuroexcitatory action is thought to be mediated via interaction with the N-methyl-D-aspartate (NMDA) receptor of the glutamate family. No mechanism for quinolinic acid removal, nor for synaptic inactivation, has been found, and consequently accumulation of concentrations capa_x0002_ble of inducing neuronal degeneration and death may occur.
기존화학 물질 KE-29939
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고 GHS hazard pictograms
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P264 취급 후에는 손을 철저히 씻으시오.
P264 취급 후에는 손을 철저히 씻으시오.
P271 옥외 또는 환기가 잘 되는 곳에서만 취급하시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
NFPA 704
0
2 0

퀴놀린산 MSDS


Pyridine-2,3-dicarboxylic acid

퀴놀린산 C화학적 특성, 용도, 생산

화학적 성질

White powder;Light yellow powder

용도

Quinolinic acid is an endogenous NMDA agonist. Quinolinic acid is a metabolite of tryptophan that acts as a putative NMDA receptor agonist. Quinolinic acid is an ?excitotoxic? metabolite and an agonist of N-methyl-D-aspartate receptors. properties of KYNA raise the possibility of a functional link between KYNA and QUIN in the brain which may be of relevance for an understanding of human neurodegenerative disorders. Quinolinic acid is a potent endogenous excitant at amino acid receptors in CNS.

위험도

A poison by skin contact. Moderately toxic by ingestion. A mild skin irritant.

공업 용도

The use of quinolinic acid during flotation of hematite results in the adsorption of quinoline on hematite, allowing amine to selectively adsorb onto the hematite surface.

생물학적 활성

Endogenous NMDA agonist and transmitter candidate. May distinguish between NMDA receptor subtypes.

Safety Profile

A poison by skin contact. Moderately toxic by ingestion. Experimental reproductive effects. A mdd skinn irritant. When heated to decomposition it emits toxic vapors of NOx.

퀴놀린산 준비 용품 및 원자재

원자재

준비 용품


퀴놀린산 공급 업체

글로벌( 564)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Hebei Mojin Biotechnology Co., Ltd
+8613288715578
sales@hbmojin.com China 12457 58
Hebei Guanlang Biotechnology Co,.LTD
+8619930503252
daisy@crovellbio.com China 5964 58
shandong exelon biochem co.ld
+86-533-2119995 +8615053330977
451614802@QQ.com China 28 58
Frapp's ChemicalNFTZ Co., Ltd.
+86 (576) 8169-6106
sales@frappschem.com China 885 50
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806
sales@capotchem.com China 29797 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21695 55
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679 +86-18949832763
info@tnjchem.com China 2989 55
career henan chemical co
+86-0371-86658258
sales@coreychem.com China 29914 58
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715
admin@nexconn.com China 10248 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28180 58

퀴놀린산 관련 검색:

Copyright 2019 © ChemicalBook. All rights reserved