DLin-M-C3-DMA
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DLin-M-C3-DMA 속성
- 끓는 점
- 670.2±43.0 °C(Predicted)
- 밀도
- 0.886±0.06 g/cm3(Predicted)
- 저장 조건
- Sealed in dry,Room Temperature
- 용해도
- Soluble in Ethanol, DMSO, DMF
- 산도 계수 (pKa)
- 9.37±0.28(Predicted)
- 물리적 상태
- Liquid
- 색상
- Colorless to light yellow
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
DLin-M-C3-DMA C화학적 특성, 용도, 생산
개요
D-Lin-MC3-DMA (MC3, DLin-MC3-DMA) is a potent and ionizable cationic lipid. D-Lin-MC3-DMA is used for delivery of siRNA in vivo. DLin-MC3-DMA, or (6Z,9Z,28Z,31Z)-heptatriacont-6,9,28,31-tetraene-19-yl 4-(dimethylamino)butanoate , is one of the most utilized cationic lipids that is used for making Lipid Nano-Particles (LNPs). These lipids, can form nanoparticles that can encapsulate and deliver siRNA, mRNA, DNA or small molecules into the cytoplasm and represent the most advanced delivery platforms for systemic administration of active molecules.용도
DLin-M-C3-DMA is a commonly used drug delivery vehicle for the fabrication of lipid nanoparticles (LNPs), which exert therapeutic effects by encapsulating and delivering siRNA, mRNA, DNA, or small molecules into the cytoplasm of the cell, and is a potent siRNA delivery vehicle.생물학적 활성
DLin-MC3-DMA is an ionizable lipid used in combination with other lipids for encapsulation of RNA and DNA into lipid nanoparticles (LNPs). Administration of DLin-MC3-DMA based LNPs have delivered siRNA and reduced Factor VII levels in mice. Delivery of BCR-ABL siRNA reduced leukemic burden in a mouse model of chronic myeloid leukemia (CML).DLin-M-C3-DMA 준비 용품 및 원자재
원자재
6,9,28,31-Heptatriacontatetraen-19-ol, (6Z,9Z,28Z,31Z)-
4-DIMETHYLAMINOBUTYRIC ACID HYDROCHLORIDE
CIS,CIS-9,12-OCTADECADIENOL
9,12-Octadecadien-1-ol, methanesulfonate, (9Z,12Z)-
4-(Dimethylamino)butanoic acid
준비 용품
DLin-M-C3-DMA 공급 업체
글로벌( 138)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
XIAMEN SINOPEG BIOTECH CO., LTD. | +86-0592-7761068 +8617350879715 |
changaiwei@sinopeg.com | China | 59 | 58 |
BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12452 | 58 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 14936 | 58 |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 |
figo.gao@foxmail.com | China | 8136 | 58 |
Shochem(Shanghai) Co.,Ltd | 86-21-50800795 |
info@shochem.com | CHINA | 288 | 58 |
career henan chemical co | +86-0371-86658258 15093356674; |
factory@coreychem.com | China | 29826 | 58 |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 |
sale04@alfachem.cn | China | 12321 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 |
sales@hzclap.com | CHINA | 6313 | 58 |