콘드로이틴황산나트륨

콘드로이틴황산나트륨
콘드로이틴황산나트륨 구조식 이미지
카스 번호:
24967-93-9
한글명:
콘드로이틴황산나트륨
동의어(한글):
소듐콘드로이틴설페이트
상품명:
Chondroitin 4-sulfate
동의어(영문):
turkadon;Chodroitin Sulfate;chondroitinasulfate;ChondroitinSulphateA;Chondroitine sulfate;CHONDROITIN SULFATE A;CHONDROITIN-4-SULFATE;chondroitinsulfatetypea;CSAChondroitin-4-sulfate;chondroitinsulfuricacida
CBNumber:
CB7352434
분자식:
(C14H19NO14SNa2)n
포뮬러 무게:
499.38
MOL 파일:
Mol file

콘드로이틴황산나트륨 속성

알파
D -28 to -32°
저장 조건
2-8°C
용해도
H2O: 0.1 g/mL, 약간 흐릿함, 희미한 노란색

안전

WGK 독일 3
F 고인화성물질 3-10
독성 mouse,LD,oral,> 15gm/kg (15000mg/kg),Zhonghua Yixue Zazhi. Chinese Medical Journal. Vol. 58, Pg. 739, 1978.

콘드로이틴황산나트륨 C화학적 특성, 용도, 생산

개요

Chondroitin 4-sulfate is a natural polymer of a disaccharide consisting of glucuronic acid and N-acetyl glucosamine which is sulfated either in the 4 or 6 position. It is a glycosaminoglycan considered as a symptomatic slow-acting drug for osteoarthritis (SYSADOA).

화학적 성질

White or yellowish amorphous powder. Tasteless, odorless, hygroscopic, soluble in water, insoluble in organic solvents such as ethanol, acetone, ether, etc. Optical rotation -25°-+35°(c=1, H2O). There are characteristic absorption peaks at 725cm-1, 852cm-1 and 930cm-1 by infrared spectroscopy.

용도

sodium chondroitin sulfate is described as a skin-conditioning agent, with possible anti-inflammatory properties. It can be found in such products as moisturizers and night skin care preparations. It is a derivative of natural mucopolysaccharides. Chondroitin 4-sulfate is an important structural component of cartilage and has been used as a dietary supplement to treat symptoms of joint discomfort.

정의

ChEBI: Chondroitin 4'-sulfate is a chondroitin sulfate in which the site of sulfation is carbon 4 of the N-acetylgalactosamine (GalNAc) sugar. It has a role as a mouse metabolite. It is a conjugate acid of a chondroitin 4'-sulfate anion.

참고 문헌

1. Inhibition of Spiral Growth and Dissolution at the Brushite (010) Interface by Chondroitin 4-Sulfate. DOI:10.1021/acs.jpcb.8b11531
2. Evaluation of Chitosan-Based Films Containing Gelatin, Chondroitin 4-Sulfate and ZnO for Wound Healing. DOI:10.1007/s12010-017-2462-z
3. Expression and function of chondroitin 4‐sulfate and chondroitin 6‐sulfate in human glioma. DOI:10.1096/fj.201901621RRR
4. https://pubchem.ncbi.nlm.nih.gov/compound/70678540

콘드로이틴황산나트륨 준비 용품 및 원자재

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