FMOC-ARG(ME,PBF)-OH

FMOC-ARG(ME,PBF)-OH 구조식 이미지
카스 번호:
1135616-49-7
상품명:
FMOC-ARG(ME,PBF)-OH
동의어(영문):
Fmoc-Arg(Me,Pbf);FMoc-Arg(Pbf,Me)-OH;FMOC-ARG(ME,PBF)-OH;FMOC-ARG(ME,PBF)-OH 1 G;Fmoc-Arg(Me,Pbf)-OH, >97%;(9H-Fluoren-9-yl)MethOxy]Carbonyl Arg(Me,Pbf)-OH;Nα-Fmoc-Nω-methyl-Nω'-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine;Nα-Fmoc-Nω-methyl-Nω'-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine≥ 98% (HPLC);N-ALPHA-FMOC-N-OMEGA-METHYL-N-OMEGA'-(2,2,4,6,7-PENTAMETHYLDIHYDROBENZOFURAN-5-SULFONYL)-L-ARGININE;N-alpha-Fmoc-N-omega-methyl-N-omega’-(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-sulfonyl)-L-arginine
CBNumber:
CB7353981
분자식:
C35H42N4O7S
포뮬러 무게:
662.8
MOL 파일:
Mol file

FMOC-ARG(ME,PBF)-OH 속성

밀도
1.33
저장 조건
Store at -15°C to -25°C.
산도 계수 (pKa)
3.80±0.21(Predicted)

안전

FMOC-ARG(ME,PBF)-OH C화학적 특성, 용도, 생산

개요

FMOC-Arg (ME, PBF)-OH is a kind of protected form of arginine. Arginine is double-protected by butyloxycarbonyl (BOC) and 2, 2, 4, 6, 7-pentamethyldihydrobenzofuran-5-sulfonyl (PBF). It is a derivative for introducing mono-methyl-arginine during Fmoc SPPS. Coupling can be carried out using any standard activation method. PBF protecting group can be removed by TFA-mediated cleavage reaction. As a kind of protected amino acid, it is an important intermediate in various fields such as peptide synthesis, asymmetric synthesis, medicinal chemistry as well as polymer chemistry.

화학적 성질

White powder

용도

Fmoc-?Arg(Me,?pbf)?-?OH can be used as reactant/reagent in design, synthesis and structure-activity relationship of macrocyclic peptidomimetics that bind to WDR5 and block WDR5-MLL protein-protein interaction.

참고 문헌

https://www.merckmillipore.com/CN/zh/product/Fmoc-Arg%28Me%2CPbf%29-OH,MDA_CHEM-852105?ReferrerURL=https%3A%2F%2Fguge6.firstguo.com%2F&bd=1
https://en.wikipedia.org/wiki/Peptide_synthesis
Kim, Tae-il, et al. "Arginine-conjugated polypropylenimine dendrimer as a non-toxic and efficient gene delivery carrier." Biomaterials 28.11 (2007): 2061-2067.

FMOC-ARG(ME,PBF)-OH 준비 용품 및 원자재

원자재

준비 용품


FMOC-ARG(ME,PBF)-OH 공급 업체

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