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EMBELIN

EMBELIN 구조식 이미지

카스 번호:: 550-24-3

상품명:: EMBELIN

동의어(영문):: EMBELIN;emberine;NSC 91874;embelicacid;Embelin, >98%;XIAP INHIBITOR;EMbeliaquinone;TIMTEC-BB SBB005949;Embelin (Embelic acid);APOPTOSIS ACTIVATOR III

CBNumber:: CB7365074

분자식:: C17H26O4

포뮬러 무게:: 294.39

MOL 파일:: 550-24-3.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 183

EMBELIN 속성

녹는점: 142-143°C

끓는 점: 356.15°C (rough estimate)

밀도: 1.131

굴절률: 1.4230 (estimate)

저장 조건: Keep in dark place,Inert atmosphere,2-8°C

용해도: DMSO: >10mg/mL

물리적 상태: 고체

물리적 상태: 단단한 모양

산도 계수 (pKa): 2.84±0.50(Predicted)

색상: 다크 오렌지

감도: Light Sensitive

안정성: 제공된 대로 구매일로부터 1년 동안 안정적입니다. DMSO 또는 에탄올 용액은 -20°C에서 최대 1개월 동안 보관할 수 있습니다.

LogP: 5.024 (est)

안전

WGK 독일	3
RTECS 번호	DK4230000

EMBELIN C화학적 특성, 용도, 생산

화학적 성질

Orange Solid

용도

Embelin is a natural benzoquinone found in plants of the Myrsinaceae family. Embelin has a wide range of biological activity as it inhibits the growth of bacteria, fungi, protozoa and parasites. Embel in also displays contraceptive and pro-apoptotic properties.

정의

ChEBI: A member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxy-1,4-benzoquinone which is substituted by an undecyl group at position 3. Isolated from Lysimachia punctata and Embelia ribes, it exhibits antimicrobial, an ineoplastic and inhibitory activity towards hepatitis C protease.

생물학적 활성

Cell-permeable, non-peptide inhibitor of X-linked inhibitor of apoptosis (XIAP) (IC 50 = 4.1 μ M in competition binding assay with Smac peptide); binds to the BIR3 domain, preventing XIAP interaction with caspase-9 and Smac. Inhibits cell growth, induces apoptosis and activates caspase-9 in prostate cancer cells (IC 50 4-6 μ M), but has a weaker effect on normal prostate cells (IC 50 = 19-20 μ M). Overcomes the protective effect of XIAP on apoptosis in XIAP-transfected Jurkat cells. Anti-tumor, analgesic and anti-inflammatory in vivo .

EMBELIN 준비 용품 및 원자재

원자재

준비 용품

ACETIC ACID 4-ACETOXY-3,6-DIOXO-5-UNDECYL-CYCLOHEXA-1,4-DIENYL ESTER

EMBELIN 공급 업체

글로벌( 183)공급 업체

공급자	전화	이메일	국가	제품 수	이점
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
Chengdu GLP biotechnology Co Ltd	028-87075086 13350802083	scglp@glp-china.com	CHINA	1824	58
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3424	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Xi'an Kono chem co., Ltd.,	029-86107037 13289246953	info@konochemical.com	China	2995	58
Shaanxi Pioneer Biotech Co., Ltd .	+8613259417953	sales@pioneerbiotech.com	China	3000	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Shanghai Standard Technology Co., Ltd.	18502101150	ft-sales@nature-standard.com	CHINA	1923	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58

EMBELIN 관련 검색:

EMBELIN EMBELIN(P),EMBELIN(RG) 2-HYDROXY-5-METHOXY-3-PENTADECYL-[1,4]BENZOQUINONE 2-HYDROXY-5-METHOXY-3-UNDECYL-[1,4]BENZOQUINONE 2,5-DIHYDROXY-3-PENTADECYL-[1,4]BENZOQUINONE ACETIC ACID 4-ACETOXY-3,6-DIOXO-5-UNDECYL-CYCLOHEXA-1,4-DIENYL ESTER 2-HYDROXY-5-METHOXY-3-TRIDECYL-[1,4]BENZOQUINONE 2,5-DIHYDROXY-3-METHYL-6-NONADECYL-[1,4]BENZOQUINONE 2,5-DIMETHOXY-3-METHYL-6-((E)-NONADEC-14-ENYL)-[1,4]BENZOQUINONE 2,5-DIMETHOXY-3-METHYL-6-NONADECYL-[1,4]BENZOQUINONE ACETIC ACID 4-ACETOXY-2-METHYL-5-((E)-NONADEC-14-ENYL)-3,6-DIOXO-CYCLOHEXA-1,4-DIENYL ESTER ILIMAQUINONE MAESAQUINONE RAPANONE ACETIC ACID 4-HYDROXY-2-METHYL-5-((E)-NONADEC-14-ENYL)-3,6-DIOXO-CYCLOHEXA-1,4-DIENYL ESTER 2,5-DIMETHOXY-3-UNDECYL-[1,4]BENZOQUINONE ACETIC ACID 4-HYDROXY-3,6-DIOXO-5-UNDECYL-CYCLOHEXA-1,4-DIENYL ESTER 2-HYDROXY-5-METHOXY-6-METHYL-3-((E)-NONADEC-14-ENYL)-[1,4]BENZOQUINONE