A dye used to stain nucleic
acids. It fluoresces at 530 nm when intercalated into double
stranded DNA, or at 640 nm when ionically bound to single
stranded DNA. It produces mutations, some involving reading
frame shifts, other deletions or insertions and is carcinogenic.
It is also known to be a dermal phototoxicant.
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H341
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Fluorescent stain for nucleic acids. An RNA polymerase inhibitorAcridine Orange acts as a lysosomal dye. It is used for cell-cycle studies. It plays an important role as a nucleic acid-selective fluorescent cationic dye, which is useful for cell cycle determination. Further, it serves as an inhibitor of RNA polymerase.
일반 설명
Acridine orange is a metachromatic fluorescent cationic dye that permeates the cell membrane and intercalates DNA and RNA. It allows for visual detection of nucleic acids on agarose and polyacrylamide gels.
