SCOULERIN

SCOULERIN 구조식 이미지
카스 번호:
6451-73-6
상품명:
SCOULERIN
동의어(영문):
SCOULERIN;Scoreline;l-skoulerine;l-scoulerine;SCOULERIN(SH);Alkaloid HF-1;SCOULERIN(RG);(-)-scoulerine;(-)-Scoulerine;2,9-DIOXY-3,10-DIMETHOXYBERBINE
CBNumber:
CB7382903
분자식:
C19H21NO4
포뮬러 무게:
327.37
MOL 파일:
6451-73-6.mol

SCOULERIN 속성

녹는점
192°C
끓는 점
503.3±50.0 °C(Predicted)
밀도
1.37±0.1 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
DMSO에 용해됨
물리적 상태
결정성 고체
산도 계수 (pKa)
9.88±0.20(Predicted)

안전

SCOULERIN C화학적 특성, 용도, 생산

개요

This form of the alkaloid is more widespread than the d-form, occurring in Corydalis caseana, C. micrantha, C. montana, C. scouleri, C. sibirica and Papaver somniferum. It has [α]26D - 318° (c 0.41, MeOH) or - 289° (c 0.62, MeOH). It forms pale grey needles when crystallized from MeOH. The hydrochloride has m.p. 268-9°C; the picrate, m.p. 206°C (dec.) and the diethyl ether, m.p. 155°C. The oxidation products are the same as for the preceding base.

화학적 성질

Off-White to Pale Pink Solid

용도

(S)-Scoulerine is an alkaloid found in the opium poppy. (S)-Scoulerine acts as an antagonist at the α2-adrenoceptor, α1D-adrenoceptor and 5-HT receptor.

정의

ChEBI: A berberine alkaloid isolated from Corydalis saxicola.

참고 문헌

Manske., Can. J. Res., 14B, 347, 354 (1936)
Manske., ibid, 17B, 57 (1939)
Manske., ibid, 18B, 414 (1940)
Manske., ibid, 20B, 49 (1942)
Brochmann-Hanssen, Nielsen., Tetrahedron Lett., 2261 (1966)
Synthesis:
Kametani., Japanese Patent, 70, 37,976, 10 December 1970

SCOULERIN 준비 용품 및 원자재

원자재

준비 용품


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