Tazarotene is a prescription topical retinoid sold as a cream or gel. This medication is approved for treatment of psoriasis, acne, and sun damaged skin (photodamage). It is commonly sold in two concentrations: 0.05% and 0.1%. In addition to tretinoin, wh
정의
ChEBI: The ethyl ester of tazarotenic acid. A prodrug for tazarotenic acid, it is used for the treatment of psoriasis, acne, and sun-damaged skin.
Indications
Like other retinoids, tazarotene (Tazorac) acts by binding
to RARs and altering gene expression. Tazarotene
appears to be particularly selective for the retinoid receptors
RAR-β and RAR-γ, but the clinical significance
of this observation is unknown.
Clinical Use
In the United States, tazarotene has been approved
for topical treatment of psoriasis (involving up to 20%
body surface area) and mild to moderate facial acne.
Application site burning, stinging, and desquamation are
common side effects, especially with acne. Tazarotene is
contraindicated in women who are pregnant.
부작용
Tazorac is a category X drug and must be avoided in pregnancy. This drug
can be irritating and should be avoided in patients with sensitive skin or
seborrheic dermatitis.
