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P405
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ISOGUVACINE HYDROCHLORIDE C화학적 특성, 용도, 생산
개요
This base is isolated, together with Guvacine (q.v.) from the nuts of Areca
catechu. It is optically inactive and yields crystalline salts: the hydrochloride,
m.p. 231°C; aurich1oride, m.p. 198- 200°C and the p1atinich1oride, m.p. 235°C.
The alkaloid is faintly acid to litmus and on methylation gives the N-methyl
derivative which, on more vigorous methylation yields the dimethyl compound
giving a crystalline platinichloride, m.p. 252°C. The above melting points suggest
that the base may be mainly Arecaidine (q.v.) but on distillation with Zn dust,
it yields products with the characteristic pyrrole reaction.
