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2'-Deoxycytidine

2'-Deoxycytidine 구조식 이미지

카스 번호:: 951-77-9

상품명:: 2'-Deoxycytidine

동의어(영문):: DC;deoxycytidine;4-AMino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)pyriMidin-2(1H)-one;dCyd;2-Deoxycystidine;Cytosine deoxyribonucleoside;4-amino-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-pyrimidin-2-one;2'-DC;2'Isomer Only)

CBNumber:: CB7452978

분자식:: C9H13N3O4

포뮬러 무게:: 227.22

MOL 파일:: 951-77-9.mol

MSDS 파일:: SDS

속성

안전

MSDS

용도

공급 업체 459

2'-Deoxycytidine 속성

녹는점: 209-211 °C(lit.)

끓는 점: 368.93°C (rough estimate)

밀도: 1.3171 (rough estimate)

굴절률: 59 ° (C=1, H2O)

저장 조건: -20°C

용해도: H₂O: 50 mg/mL, 투명, 무색

물리적 상태: 결정성 분말

산도 계수 (pKa): 14.03±0.60(Predicted)

색상: 하얀색

수용성: 물에 불용성, DMSO.

BRN: 87567

InChI: InChI=1S/C9H13N3O4/c10-7-1-2-12(9(15)11-7)8-3-5(14)6(4-13)16-8/h1-2,5-6,8,13-14H,3-4H2,(H2,10,11,15)/t5-,6+,8+/m0/s1

InChIKey: CKTSBUTUHBMZGZ-SHYZEUOFSA-N

SMILES: OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)C[C@@H]1O

CAS 데이터베이스: 951-77-9(CAS DataBase Reference)

NIST: Deoxycytidine(951-77-9)

EPA: Cytidine, 2'-deoxy- (951-77-9)

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

안전지침서	24/25
WGK 독일	3
RTECS 번호	HA3800000
F 고인화성물질	10
TSCA	Yes
HS 번호	29349990

그림문자(GHS):

신호 어:

Warning

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	P- 코드
H315	피부에 자극을 일으킴	피부부식성 또는 자극성물질	구분 2	경고	P264, P280, P302+P352, P321,P332+P313, P362
H319	눈에 심한 자극을 일으킴	심한 눈 손상 또는 자극성 물질	구분 2A	경고	P264, P280, P305+P351+P338,P337+P313P
H335	호흡 자극성을 일으킬 수 있음	특정 표적장기 독성 - 1회 노출;호흡기계 자극	구분 3	경고

예방조치문구:

P280	보호장갑/보호의/보안경/안면보호구를 착용하시오.
P302+P352	피부에 묻으면 다량의 물로 씻으시오.
P304+P340	흡입하면 신선한 공기가 있는 곳으로 옮기고 호흡하기 쉬운 자세로 안정을 취하시오.

NFPA 704

	0
1		0

2'-Deoxycytidine MSDS

2'-Deoxycytidine monohydrate

2'-Deoxycytidine C화학적 특성, 용도, 생산

화학적 성질

White crystalline powder

용도

A deoxyribonucleoside

정의

ChEBI: A pyrimidine 2'-deoxyribonucleoside having cytosine as the nucleobase.

일반 설명

2′-Deoxycytidine (deoxyC) is one of the deoxynucleosides containing cytosine as the nucleobase. It is found in the blood, feces, and urine.

Safety Profile

Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

Purify 2'-deoxycytidine by recrystallisation from MeOH/Et2O or EtOH and dry it in air. [NMR: Miles J Am Chem Soc 85 1007 1963, UV: Fox & Shugar Biochim Biophys Acta 9 369 1952.] The hydrochloride crystallises from H2O/EtOH and has m 174o(dec, 169-173o). [Walker & Butler Can J Chem 34 1168 1956.] The picrate has m 208o(dec). [Fox et al. J Am Chem Soc 83 4066 1961, Beilstein 25 III/IV 3662.]

Structure and conformation

2'-Deoxycytidine monohydrate (dCMP) is a nucleoside phosphate in being comprised of a deoxyribonucleoside and one phosphate group. It has a deoxyribose as its sugar constituent with one phosphate group attached. Its nucleoside contains a pyrimidine base, i.e., a cytosine attached to the deoxyribose sugar. It has only one phosphate group attached to the nucleoside. Its conjugate acid form is deoxycytidylic acid, whereas its conjugate base form is deoxycytidylate. dCMP, instead of having a hydroxyl group on the 2′ carbon of the sugar component as it is in Cytidine monophosphate (CMP), has it reduced to a hydrogen atom (thus, deoxy- in its name). dCMP is one of the monomeric units that constitute DNA, whereas CMP is one of the monomeric units that make up RNA.

2'-Deoxycytidine 준비 용품 및 원자재

원자재

준비 용품

2-AMino-9-[5-(hydroxyMethyl)oxolan-2-yl]-3H-purin-6-one 2'-Deoxycytidine-5'-monophosphoric acid DMT-DCYTIDINE (N6-BENZOYL) CYANOETHYL PHOSPHORAMIDITE) 5'-O-(4,4'-DIMETHOXYTRITYL)-N4-ACETYL-2'-DEOXYCYTIDINE PHTHALAMIDE 5-Bromo-2'-deoxycytidine N4-벤조일-5'-O-(4,4'-디메톡시트리틸)-2'데옥시시티딘 5-Iodo-2'-deoxycytidine

2'-Deoxycytidine 공급 업체

글로벌( 459)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Yunbio Tech Co.,Ltd.	+86-010-60605551 +86-18046518538	yunbiochem@126.com	China	321	58
Chemtour Biotech Co., Ltd	+8617327281506	market@chemtour.com	China	1472	58
SHANGHAI NOVRIBO BIOTECH	17821030819	June.Liu@Desano.com	China	73	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12453	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15371	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1807	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58

2'-Deoxycytidine 관련 검색:

시토신 플루시토신 p-토루엔 술폰산 일수화물 5-플루오로-2'-디옥시유리딘 시틴딘 N4-벤조일-5'-O-(4,4'-디메톡시트리틸)-2'데옥시시티딘 시티딘 황산염 시티콜린나트륨 MELIBIOSE LACTOSE, MONOHYDRATE Levofloxacin heMihydrate N4-Acetylcytidine CYTIDINE 3'-MONOPHOSPHATE 5-METHYLCYTIDINE (+)-3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)cytidine DNA polymeraseⅠfrom E.coli DMT-dC(bz) Phosphoramidite N-Benzoyl-2'-deoxy-cytidine