ChemicalBook >제품 카탈로그 >생화학 공학>식물 추출물>4-아미노안티피린

4-아미노안티피린

4-아미노안티피린 구조식 이미지

카스 번호:: 83-07-8

한글명:: 4-아미노안티피린

동의어(한글):: 4-아미노-1,5-디메틸-2-페닐-3H-파라졸3-온;4-아미노안티피린;암피론;암모늄수산화물;암모니아액체;암모니아용액;수화암모니아;암모니아물;암모니아수;수산화;4-아미노안티피렌;1,2-다이하이드로-1,5-다이메틸-2-페닐-4-아미노-3H-피라졸-3-온;1-페닐-2,3-다이메틸-4-아미노-5-피라졸론;3H-피라졸-3-온, 4-아미노-1,2-다이하이드로-1,5-다이메틸-2-페닐-;4-아미노-1,2-다이하이드로-1,5-다이메틸-2-페닐-3H-피라졸-3-온;4-아미노-1,5-다이메틸-2-페닐-3-피라졸론;4-아미노-2,3-다이메틸-1-페닐-5-피라졸론;안티피린, 4-아미노-

상품명:: 4-Aminoantipyrine

동의어(영문):: 4-AAP;AMPYRONE;AMINOANTIPYRINE;4-AMINOPHENAZONE;4-Amino-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one;4-AMINOANTIPYRIN;4-AMINO-2,3-DIMETHYL-1-PHENYL-3-PYRAZOLIN-5-ONE;4-AMINO-1,5-DIMETHYL-2-PHENYL-1,2-DIHYDRO-PYRAZOL-3-ONE;NSC 60242;Minoazophene

CBNumber:: CB7485059

분자식:: C11H13N3O

포뮬러 무게:: 203.24

MOL 파일:: 83-07-8.mol

MSDS 파일:: SDS

속성

안전

MSDS

용도

공급 업체 398

4-아미노안티피린 속성

녹는점: 105-110 °C(lit.)

끓는 점: 340 C

밀도: 0.8

굴절률: 1.4930 (estimate)

저장 조건: Keep in dark place,Inert atmosphere,Room temperature

용해도: H₂O: 0.1 g/mL, 투명

산도 계수 (pKa): pK1: 4.94(+1) (25°C)

물리적 상태: 분말 또는 결정

색상: 노란색에서 황갈색

수소이온지수(pH): 7.1 (100g/l, H2O, 20℃)(slurry)

냄새: 냄새 없는

수용성: ca. 500g/L(20℃)

Merck: 14,591

BRN: 181635

안정성: 안정적인. 빛에 민감할 수 있습니다.

LogP: -0.257 (est)

CAS 데이터베이스: 83-07-8(CAS DataBase Reference)

NIST: Aminoantipyrene(83-07-8)

EPA: 4-Aminoantipyrene (83-07-8)

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

위험품 표기	Xn
위험 카페고리 넘버	22-36/37/38-20/21/22
안전지침서	26-36-36/37/39
WGK 독일	3
RTECS 번호	CD2480000
F 고인화성물질	8-9-23
위험 참고 사항	Harmful
TSCA	Yes
HS 번호	29331190
독성	LD50 orally in Rabbit: 1700 mg/kg
기존화학 물질	KE-01297

그림문자(GHS):

신호 어:

Warning

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	그림 문자	P- 코드
H302	삼키면 유해함	급성 독성 물질 - 경구	구분 4	경고		P264, P270, P301+P312, P330, P501

예방조치문구:

P264	취급 후에는 손을 철저히 씻으시오.
P264	취급 후에는 손을 철저히 씻으시오.
P270	이 제품을 사용할 때에는 먹거나, 마시거나 흡연하지 마시오.
P301+P312	삼켜서 불편함을 느끼면 의료기관(의사)의 진찰을 받으시오.
P501	...에 내용물 / 용기를 폐기 하시오.

NFPA 704

	1
2		1

4-아미노안티피린 MSDS

Ampyrone

4-아미노안티피린 C화학적 특성, 용도, 생산

화학적 성질

Amber crystalline powder

주요 응용

4-aminoantipyrine is the most widely used analytical reagent for the estimation of phenol. It is used as a reagent for glucose determination in the presence of peroxidase and phenol. It is also used as indicator for trace phenol determinations in water.
Phenolic compounds were determined by buffering the sample to a pH of 10.0 and adding 4-aminoantipyrine to produce a yellow or amber colored complex in the presence of ferricyanide ion. The colour is intensified through extraction of the complex into chloroform. Measurement of this colour quantitatively determines the phenol concentration of the sample.

용도

4-Aminoantipyrine is a metabolite of aminopyrine, having both analgesic and anti-inflammatory properties. It readily forms metal complexes due to its amino nitrogen, a strong coordination site.
4-aminoantipyrine forms Schiff bases when treated with aldehydes/ketones, which are used in chemosensing applications.
Coupling Reagent for Trinder's reagent in colorimetric hydrogen peroxide detectionassays.
Forms highly stable dyes by coupling with Trinder's reagent in presence of Peroxidase and H2O2. Therefore suitable for use in test strip and solution diagnostics.

제조 방법

synthesis of 4-aminoantipyrine: Antipyrine is nitrosated by sodium nitrite, reduced by ammonium bisulfite and ammonium sulfite, hydrolyzed by sulfuric acid, and finally neutralized with liquid ammonia to obtain 4-aminoantipyrine.

정의

ChEBI: 4-aminoantipyrine is a pyrazolone, a member of the class of pyrazoles that is antipyrine substituted at C-4 by an amino group. It is a metabolite of aminopyrine and of metamizole. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic, an antirheumatic drug, a peripheral nervous system drug, an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor, an antipyretic, a drug metabolite and a marine xenobiotic metabolite. It is a primary amino compound and a pyrazolone. It derives from an antipyrine.

일반 설명

4-Aminoantipyrine forms heterocyclic Schiff bases, by reaction with various aldehydes and oximes. These Schiff bases form stable complexes with transition metals.

Purification Methods

It crystallises from EtOH or EtOH/ether. [Beilstein 25 III/IV 3554.]

4-아미노안티피린 준비 용품 및 원자재

원자재

이아황산 암모늄, 고체 Iodine solution 아질산 나트륨 안티피린 Starch paper 황산 2,3-dimethyl-4-nitroso-1-phenyl-3-pyrazolin-5-one

준비 용품

Aminopyrine N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)formamide 1,2-dihydro-1,5-dimethyl-4-(methylamino)-2-phenyl-3H-pyrazol-3-one 암모늄 알긴염 Ramifenazone N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-3-methoxybenzamide 2-CYANO-N-(1,5-DIMETHYL-3-OXO-2-PHENYL-2,3-DIHYDRO-1H-PYRAZOL-4-YL)-ACETAMIDE 3-CHLORO-N-(1,5-DIMETHYL-3-OXO-2-PHENYL-2,3-DIHYDRO-1H-PYRAZOL-4-YL)PROPANAMIDE AMINOPROPYLON

4-아미노안티피린 공급 업체

글로벌( 398)공급 업체

공급자	전화	이메일	국가	제품 수	이점
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24738	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
hebei hongtan Biotechnology Co., Ltd	+86-86-1913198-3935 +8617331935328	sales03@chemcn.cn	China	951	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9348	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58