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Thymopentin

Thymopentin 구조식 이미지

카스 번호:: 69558-55-0

상품명:: Thymopentin

동의어(영문):: TP-5;RKDVY;Immunox;Timunox;ORF-15244;THYMOPETIN;Thyopentin;THYMOPENTIN;Thymopentine;ThymopentinⅡ

CBNumber:: CB7491069

분자식:: C30H49N9O9

포뮬러 무게:: 679.77

MOL 파일:: 69558-55-0.mol

속성

안전

용도

공급 업체 394

Thymopentin 속성

밀도: 1.44±0.1 g/cm3(Predicted)

저장 조건: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

용해도: DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 10 mg/ml

물리적 상태: 가루

산도 계수 (pKa): 3.07±0.10(Predicted)

색상: 하얀색

CAS 데이터베이스: 69558-55-0(CAS DataBase Reference)

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

WGK 독일	3
HS 번호	3504009000

그림문자(GHS):

신호 어:

Warning

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	그림 문자	P- 코드
H302	삼키면 유해함	급성 독성 물질 - 경구	구분 4	경고		P264, P270, P301+P312, P330, P501

예방조치문구:

P264	취급 후에는 손을 철저히 씻으시오.
P264	취급 후에는 손을 철저히 씻으시오.
P270	이 제품을 사용할 때에는 먹거나, 마시거나 흡연하지 마시오.
P301+P312	삼켜서 불편함을 느끼면 의료기관(의사)의 진찰을 받으시오.
P330	입을 씻어내시오.
P501	...에 내용물 / 용기를 폐기 하시오.

NFPA 704

	0
2		0

Thymopentin C화학적 특성, 용도, 생산

개요

Thymopentin is a kind of peptide. Peptides and polypeptides play a critical role in the immune system and are therefore predestined as a source for new approaches in immunotherapy. Thymopentin is capable of modulating the immune response. It is a fragment of the thymopoietins (TMPOs) which is a family of nuclear protein. Studies have shown that Thymopentin is capable of affecting the function of T cells and monocytes monitored by increased cGMP level and the triggering of cellular signaling. It is also capable of improve an imbalanced immune system. As an immunomodulating agent, it is clinically used in the treatment of autoimmune diseases such as atopic dermatitis, chronic lymphocytic leukemia, Sezary’s syndrome, rheumatoid arthritis and decreased immune competency. Recent study has also shown that its immuno-modulating effect can also help fight against the infection of mycobacterium tuberculosis.

용도

Thymopentin Acetate (TP-5) is a synthetic immunomodulating pentapeptide.

Clinical Use

Thymopentin is a synthetic, immunomodulating pentapeptide, representing the active fragment of the thymus hormone, thymopoietin. Thymopentin induces phenotypic differentiation and maturation of T-cells. It appears of value in the treatment of primary immune deficiency, rheumatoid arthritis, atopic dermatitis, sarcoidosis and a variety of other diseases with manifestations of disturbed immune balance.

참고 문헌

Zhang, Yan, et al. "Novel thymopentin release systems prepared from bioresorbable PLA–PEG–PLA hydrogels." International journal of pharmaceutics 386.1 (2010): 15-22.
Gonser, S., E. Weber, and G. Folkers. "Peptides and polypeptides as modulators of the immune response: thymopentin—an example with unknown mode of action." Pharmaceutica Acta Helvetiae 73.6 (1999): 265-273.
Wang, Ying, et al. "Synthetic modifications of the immunomodulating peptide thymopentin to confer anti-mycobacterial activity." Biomaterials 35.9 (2014): 3102-3109.

Thymopentin 준비 용품 및 원자재

원자재

AMBERLITE(R) IRC-50 SEPHADEX G-75 ANION EXCHANGE RESIN 717

준비 용품

Thymopentin 공급 업체

글로벌( 394)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Henan Tengmao Chemical Technology Co. LTD	+8615238638457	salesvip2@hntmhg.com	China	415	58
Nantong Guangyuan Chemicl Co,Ltd	+undefined17712220823	admin@guyunchem.com	China	616	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Beijing Yibai Biotechnology Co., Ltd	0086-182-6772-3597	sales04@yibaibiotech.com	CHINA	419	58

Thymopentin 관련 검색:

THYMOPOIETIN II (33-36) Thymosin α1 Thymosin beta 4 Sermorelin Nesiritide acetate Triptorelin acetate Pramlintide acetate GLP-1 (7-37) Eptifibatide Thymalfasin THYMOPENTIN 5,THYMOPOIETIN PENTAPEPTIDE,ARG-LYS-ASP-VAL-TYR,arg-lys-asp-val-tyr acetate,H-ARG-LYS-ASP-VAL-TYR-OH THYMOPOIETIN II (32-35) THYMOPOIETIN II (32-34) THYMOPOIETIN II (34-36) THYMOSIN BETA10 (HUMAN, RAT) GLY-GLU-GLN-ARG-LYS-ASP-VAL-TYR-VAL-GLN-LEU-TYR-LEU H-ARG-LYS-ASP-VAL-TYR-OET,ARG-LYS-ASP-VAL-TYR-OET H-SER-ASP-ALA-ALA-VAL-ASP-THR-SER-SER-GLU-ILE-THR-THR-LYS-ASP-LEU-LYS-GLU-LYS-LYS-GLU-VAL-VAL-GLU-GLU-ALA-GLU-ASN-OH