Bipariden
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Bipariden 속성
- 녹는점
- 114°C
- 끓는 점
- 451.49°C (rough estimate)
- 밀도
- 1.0202 (rough estimate)
- 굴절률
- 1.5614 (estimate)
- 저장 조건
- 2-8°C
- 용해도
- 클로로포름(약간 용해됨), DMSO(약간 용해됨, 초음파 처리), 메탄올(약간 용해됨, 초음파 처리)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 14.05±0.29(Predicted)
- 색상
- 흰색에서 황백색까지
- 수용성
- 25.1mg/L
- NIST
- Biperiden(514-65-8)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 유해 물질 데이터 | 514-65-8(Hazardous Substances Data) | ||
|---|---|---|---|
| 독성 | LD50 in mice (mg/kg): 195 s.c., 56 i.v. (Klavehn) |
| 그림문자(GHS): |
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| 신호 어: | Warning | ||||||||||||||
| 유해·위험 문구: |
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| 예방조치문구: |
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Bipariden C화학적 특성, 용도, 생산
용도
amoebicide정의
ChEBI: N-Propylpiperidine in which the methyl hydrogens are substituted by hydroxy, phenyl, and 5-norbornen-2-yl groups. A muscarinic antagonist affecting both the central and peripheral nervous systems, it is used in the treatment of all form of Parkinson's disease.일반 설명
Biperiden,α-5-norbornen-2-yl- -phenyl-1-piperidinepropanol (Akineton), introduced in 1959,has a relatively weak visceral anticholinergic, but a strongnicotinolytic, action in terms of its ability to block nicotineinducedconvulsions. Therefore, its neurotropic action israther low on intestinal musculature and blood vessels. It hasa relatively strong musculotropic action, which is aboutequal to that of papaverine, in comparison with most syntheticanticholinergic drugs. Its action on the eye, althoughmydriatic, is much lower than that of atropine. These weakanticholinergic effects add to its usefulness in Parkinson syndromeby minimizing side effects.Clinical Use
Biperiden is used in all types of Parkinson disease (postencephalitic,idiopathic, arteriosclerotic) and helps toeliminate akinesia, rigidity, and tremor. It is also usedin drug-induced extrapyramidal disorders to eliminatesymptoms and permit continued use of tranquilizers.Biperiden is also of value in spastic disorders not related toparkinsonism, such as multiple sclerosis, spinal cord injury,and cerebral palsy. It is contraindicated in all formsof epilepsy.Safety Profile
Poison by ingestion,subcutaneous, intraperitoneal, and intravenous routes.When heated to decomposition, it emits toxic fumes ofNOx.Bipariden 준비 용품 및 원자재
원자재
준비 용품
Bipariden 공급 업체
글로벌( 96)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hubei XinRunde Chemical Co., Ltd. | +8615102730682 |
bruce@xrdchem.cn | CHINA | 566 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29888 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49392 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 |
sales@tnjchem.com | China | 34571 | 58 |
| AFINE CHEMICALS LIMITED | +86-008657185134551 +86-18958018566 |
sales@afinechem.com | China | 15394 | 58 |
| Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 |
gksales1@gk-bio.com | China | 9316 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 |
sales@sarms4muscle.com | China | 10522 | 58 |
| changzhou huayang technology co., ltd | +8615250961469 |
2571773637@qq.com | China | 9817 | 58 |