Ginkgolic acid
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Ginkgolic acid 속성
- 녹는점
- 45～48℃
- 저장 조건
- 2-8°C
- 용해도
- 클로로포름(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 흰색 고체
- 끓는 점
- 221-223 °C(Press: 4 Torr)
- 밀도
- 0.9148 g/cm3
- 산도 계수 (pKa)
- 3.08±0.30(Predicted)
- 색상
- 흰색에서 황백색까지
- InChIKey
- YXHVCZZLWZYHSA-FPLPWBNLSA-N
- LogP
- 9.269 (est)
- CAS 데이터베이스
- 22910-60-7(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38 | ||
| 안전지침서 | 22-24/25-26 | ||
| WGK 독일 | 3 | ||
| HS 번호 | 29182900 |
Ginkgolic acid C화학적 특성, 용도, 생산
개요
Ginkgolic acid is slightly toxic and is an allergen; for this reason, some sources suggest using only the standardized extract, which is standardized to the flavonoids and minimizes ginkgolic acid content.Ginkgolic acid is active against the tubercle bacillus. Elsewhere, leaf extracts are used in peripheral arterial circulation problems like arteriosclerotic angiopathy, post-thrombotic syndrome, diabetic vasoconstriction with gangrene and angina, intermittent claudication，Raynaud's disease. Extracts are inhaled for ear, nose, and throat ailments like bronchitis and chronic rhinitis.
Extracts of the leaves and fruit of Ginkgo plants have long been used in traditional medicine and have multiple potential therapeutic applications, including ameliorating dementia. However, ginkgolic acids, 2-hydroxy-6-alkylbenzoic acids related to anacardic acids, may be deleterious components in these extracts. Ginkgolic acid C15:1 is a 2-hydroxy-6-alkylbenzoic acid in which the alkyl chain contains 15 carbons and is unsaturated at the 8 position. It inhibits SUMOylation in vitro (IC50 = 3 μM) and in cells without affecting protein ubiquitination. Ginkgolic acid C15:1 directly binds the SUMO-activating enzyme E1, blocking the formation of the E1-SUMO intermediate. Ginkgolic acid C15:1 also suppresses the development of pancreatic cancer xenografts in mice.
용도
Ginkgolic acid C15:1 may be used as a reference standard in the quantitative determination of alkylphenols like ginkgolic acids in Ginkgolic extract using high performance liquid chromatography coupled with mass spectrometry(HPLC-MS).Ginkgolic acid C15:1 may be used as an analytical reference standard for the quantification of the analyte in Ginkgo biloba plant extracts, and dietary supplements using chromatography techniques.
일반 설명
Ginkgolic acid C15:1 is an alkylphenol belonging to the class of ginkgolic acids isolated from Ginkgo biloba leaves. It also shows strong allergenic properties, with carcinogenic and mutagenic activity.Ginkgolic acid 준비 용품 및 원자재
원자재
Benzoic acid, 2-(chloromethyl)-6-methoxy-, ethyl ester
2-(7-Bromoheptyloxy)tetrahydro-2H-pyran
Heptanal,7-[(tetrahydro-2H-pyran-2-yl)oxy]-
5-HYDROXY-2,2-DIMETHYL-4H-BENZO[D][1,3]DIOXIN-4-ONE
Methanesulfonic acid, 1,1,1-trifluoro-, 2,2-dimethyl-4-oxo-4H-1,3-benzodioxin-5-yl ester
1,7-Heptanediol
1-Heptanol, 7-[(tetrahydro-2H-pyran-2-yl)oxy]-
2,6-다이하이드록시벤조 산
준비 용품
Ginkgolic acid 공급 업체
글로벌( 176)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9350 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 |
scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 |
sales@biopurify.com | China | 3424 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 |
sales@dolonchem.com | CHINA | 2972 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 |
ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; |
factory@coreychem.com | China | 29826 | 58 |
Ginkgolic acid 관련 검색:
살리실산 5-설포살리실산 이수화물 아세트산 엽산 시트르산 스테아르산 1-펜타데켄 실버 아세틸아세토네이트 알루미늄 아세틸아세토네이트 코발트(II) 아세틸아세토네이트 하이드레이트
allyltrimethylammonium chloride
4-Methylsalicylic acid
Sodium sulfosalicylate
Starch Sodiilm octenylsuccinate
DODECENYLSUCCINIC ACID
Ginkgolic Acid C17:1,6-[(10Z)-Heptadecenyl]salicylic acid, Ginkgolic acid II
GINKGETIN
6-pentadecylsalicylic acid