4-Acetyl-piperidine-1-carboxylic acid tert-butyl ester
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4-Acetyl-piperidine-1-carboxylic acid tert-butyl ester 속성
- 끓는 점
- 312.4±35.0 °C(Predicted)
- 밀도
- 1.052±0.06 g/cm3(Predicted)
- 저장 조건
- Keep in dark place,Sealed in dry,Room Temperature
- 산도 계수 (pKa)
- -2.23±0.40(Predicted)
- InChI
- InChI=1S/C12H21NO3/c1-9(14)10-5-7-13(8-6-10)11(15)16-12(2,3)4/h10H,5-8H2,1-4H3
- InChIKey
- HNVBBNZWMSTMAZ-UHFFFAOYSA-N
- SMILES
- N1(C(OC(C)(C)C)=O)CCC(C(C)=O)CC1
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
4-Acetyl-piperidine-1-carboxylic acid tert-butyl ester C화학적 특성, 용도, 생산
용도
tert-Butyl 4-Acetylpiperidine-1-carboxylate is a useful research chemical.Synthesis
Tert-butyl-4-(methoxy(methyl)carbamoyl)piperidine-1-carboxylate (2.29 g, 8.32 mmol) was dissolved in 30 ml of tetrahydrofuran (THF), and the resulting solution was cooled to -78 °C. To the solution, methylmagnesium bromide (3.0 M) (7.73 ml, 10.82 mmol) was slowly added, and the solution was stirred at 0 °C for 1 hr. After the reaction was completed with a 2 N hydrochloric acid aqueous solution, 6 N sodium hydroxide solution was added to adjust the pH to 10. Then the solution was extracted with dichloromethane. The organic layer was treated with magnesium sulfate (MgSO4) and filtered, and the solution was concentrated. The resulting residue was isolated and purified by silica gel column chromatography (dichloromethane/methanol = 10/1) to give 4-Acetyl-piperidine-1-carboxylic acid tert-butyl ester (6.36 g, 94.0 percent).4-Acetyl-piperidine-1-carboxylic acid tert-butyl ester 준비 용품 및 원자재
원자재
4-(2-ETHOXYCARBONYL-ACETYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
1-Boc-4-[methoxy(methyl)carbamoyl]piperidine
메틸마그네슘브로마이드
준비 용품
4-Acetyl-piperidine-1-carboxylic acid tert-butyl ester 공급 업체
글로벌( 223)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Shanxi Tihondan Pharmaceutical Technology Co., Ltd | +8618235132063 |
sales@tihondan.com | China | 3716 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 |
sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
Anhui Dexinjia Biopharm Co., Ltd | +86-531-82375818 +86-15064153060 |
alice@jndxj.com | China | 309 | 58 |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 |
figo.gao@foxmail.com | China | 6992 | 58 |
Accela ChemBio Inc. | (+1)-858-699-3322 |
info@accelachem.com | United States | 19965 | 58 |
Changzhou Ditong Chemical Co.,Ltd | +86-0519-88299272 |
info@edengenechem.com | China | 2169 | 58 |
4-Acetyl-piperidine-1-carboxylic acid tert-butyl ester 관련 검색:
1-Piperidinecarboxylic acid, 4-[3-(dimethylamino)-1-oxo-2-propen-1-yl]-, 1,1-dim
Propanedinitrile, 2-[hydroxy(4-phenoxyphenyl)Methylene]-
Propanedinitrile, 2-[Methoxy(4-phenoxyphenyl)Methylene]-
tert-butyl 4-(3-cyano-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-7-yl)piperidine-1-carboxylate
5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile
tert-butyl 4-(3-cyano-2-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-7-yl)piperidine-1-carboxylate
Pyrazolo[1,5-a]pyrimidine-3-carboxamide, 4,5,6,7-tetrahydro-2-(4-phenoxyphenyl)-7-(4-piperidinyl)-, (7S)-
(R)-Zanubrutinib
4-PHENOXYBENZOIC ACID
Pyrazolo[1,5-a]pyrimidine-3-carbonitrile, 4,5,6,7-tetrahydro-2-(4-phenoxyphenyl)-7-(4-piperidinyl)-
Zanubrutinib
1-Boc-hexahydro-1H-azepin-4-amine
1-Boc-4-cyanopiperidine
3-AMINO-1-[(1,1-DIMETHYLETHOXY)CARBONYL]-3-PIPERIDINEACETIC ACID METHYL ESTER
tert-butyl 6-hydroxy-3-azabicyclo[3.1.0]hexane-3-carboxylate
tert-butyl 4-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate
tert-Butyl 3,8-diazabicyclo[3.2.1]octane-8-carboxylate hydrochloride
2-OXO-2,5-DIHYDRO-PYRROLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER