피부(또는 머리카락)에 묻으면 오염된 모든 의복은 벗거나 제거하시오 피부를 물로 씻으시오/샤워하시오.
P305+P351+P338
눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
NFPA 704
2
2
0
N-(tert-Butyldimethylsilyl)-N-methyl-trifluoroacetamide C화학적 특성, 용도, 생산
화학적 성질
clear colorless to slightly yellow liquid
물리적 성질
bp 168–170°C; d 1.12 g cm?3.
용도
N-(tert-Butyldimethylsilyl)-N-methyl-trifluoroacetamide is a silylating agent used in the derivatization of various organic compounds (such as amino acids) for gas chromatogography-mass spectrometry (GC-MS) analysis.
제조 방법
obtained in 91% yield by reaction of
N-methyl-2,2,2-trifluoroacetamide (1.0 equiv) in benzene and
acetonitrile (1:1 v/v) with NaH (1.0 equiv) and then with
t-BuMe2SiCl (1.2 equiv) at 4°C.
정의
ChEBI: An N-silyl compound that is N-methyltrifluoroacetamide in which the amide nitrogen is replaced by a tert-butyldimethylsilyl group.
일반 설명
N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide is a silylating reagent which replaces the active hydrogen with tert-Butyldimethylsilyl group. The tert-Butyldimethylsilyl derivatives are found to be more resistant to hydrolysis and stable compared to trimethylsilyl (TMS) derivatives. This reagent is suitable for GC-MS analysis since it produces mass spectra, which can be easily interpreted. It is widely used for the silylation of different alcohols, thiols, phenols, carboxylic acids, amines, and amides.
N-(tert-Butyldimethylsilyl)-N-methyl-trifluoroacetamide 준비 용품 및 원자재
원자재
준비 용품
N-(tert-Butyldimethylsilyl)-N-methyl-trifluoroacetamide 공급 업체
