FORTUNELLIN
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FORTUNELLIN 속성
- 녹는점
- 193-198°C
- 끓는 점
- 888.7±65.0 °C(Predicted)
- 밀도
- 1.62±0.1 g/cm3(Predicted)
- 산도 계수 (pKa)
- 6.10±0.40(Predicted)
안전
FORTUNELLIN C화학적 특성, 용도, 생산
개요
Fortunellin is a potential anti-inflammation agent in inflammatory diseases, it targets miR-374a, which is a negative regulator of phosphatase and tensin homolog (PTEN). Fortunellin protects against high fructose-induced diabetic heart injury in mice by suppressing inflammation and oxidative stress via AMPK/Nrf-2 pathway regulation.Biological Functions
Fortunellin (acacetin 7-O-neohesperidoside) is a citrus flavonoid isolated from kumquat fruit. Kumquat extract has attracted much attention recently for its beneficial effects on human health, which include antitumor, antioxidant and anti-inflammatory characteristics . The beneficial effects of flavonoids on IBD have been confirmed in many studies. However, although fortunellin is the main flavonoid in kumquat, there is a lack of information on its alleviation of IBD.Mechanism of action
Fortunellin is a citrus flavonoid that is a potential anti-inflammation agent in inflammatory diseases. Fortunellin ameliorated colitis symptoms, including excessive inflammation and oxidative stress. Fortunellin decreased epithelial cell apoptosis through inhibiting PTEN expression in colitis. Fortunellin-induced downregulation of PTEN could be counteracted by miR-374a depletion. Moreover, knockdown of miR-374a in vivo partly inhibited the effects of fortunellin on rat colitis.FORTUNELLIN 준비 용품 및 원자재
원자재
준비 용품
FORTUNELLIN 공급 업체
글로벌( 45)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Finetech Industry Limited | +86-27-87465837 +8618971612321 |
info@finetechnology-ind.com | China | 9702 | 58 |
| BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 |
support@targetmol.com | United States | 19973 | 58 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006608290; 18621169109 |
market03@meryer.com | China | 40241 | 62 |
| BOC Sciences | 1-631-485-4226; 16314854226 |
info@bocsci.com | United States | 14059 | 65 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 |
tauto@tautobiotech.com | China | 3989 | 66 |
| Finetech Industry Limited | 027-87465837 19945049750 |
sales@finetechnology-ind.com | China | 9664 | 58 |
| Wuhan ChemFaces Biochemical Co., Ltd. | 18607101326 15172504745 |
aileen@chemfaces.com | China | 7059 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 |
3008007409@qq.com | China | 27322 | 60 |
| ShangHai Biochempartner Co.,Ltd | 17754423994 17754423994 |
2853530910@QQ.com | China | 8018 | 62 |