O-ALLYLHYDROXYLAMINE HYDROCHLORIDE
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O-ALLYLHYDROXYLAMINE HYDROCHLORIDE 속성
- 녹는점
- ~170 °C (dec.)
- 저장 조건
- under inert gas (nitrogen or Argon) at 2-8°C
- 물리적 상태
- powder to crystal
- 색상
- 흰색에서 거의 흰색
- BRN
- 3552394
- InChIKey
- XIQUJVRFXPBMHS-UHFFFAOYSA-N
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
O-ALLYLHYDROXYLAMINE HYDROCHLORIDE C화학적 특성, 용도, 생산
제조 방법
To a solution of 86.8 gm (1.55 moles) of potassium hydroxide in 330 ml of absolute ethanol is added a solution of 159 gm (1.52 moles) of ethyl N-hydroxycarbamate in 330 ml of absolute ethanol. With external cooling to maintain an internal temperature of 25°C to this mixture is added 195.5 gm (1.62 moles) of allyl bromide. After the addition has been completed, the mixture is heated under reflux for 2 hr. After separating the potassium bromide formed during the reaction and washing it with absolute alcohol, the alcoholic solution is evaporated under reduced pressure. The residue is dissolved in ether and then the ether solution is extracted repeatedly with 10% aqueous sodium hydroxide solution. [From the ether solution, on evaporation 25.5 gm (18%) of ethyl N,O-diallylhydroxycar-bamate, b.p. 91-92°C (8.55 mm Hg) may be isolated.] The aqueous extract is acidified with 10% aqueous sulfuric acid and the ethyl O-allylhy-droxycarbamate is extracted with ether. Upon evaporating the ether off, 134.2 gm (61%) of the intermediate product, b.p. 107°C (12.5 mm Hg), is isolated.In a steam distillation apparatus, 134 gm of ethyl O-allylhydroxy-carbamate is treated with a solution of 120 gm of potassium hydroxide in 280 ml of water. The product is steam-distilled into a receiver containing dilute hydrochloric acid.
The steam distillate is evaporated under reduced pressure. The residue is taken up twice in absolute ethanol and dried by evaporation under reduced pressure. The yield is 91 gm (55%, overall), m.p. 169-170°C. Upon recrystallization from absolute alcohol and dry ether, the melting point is raised to 170.6-170.8°C (172-174°C). Free O-allylhydrox-ylamine has the following reported properties: b.p. 98-99°C, n25D 1.4300.
The problems connected with the preparation of O-arylhydroxylamines by this method have been attributed to the instability of the aryl- substituted aminooxy group to the hydrolytic system used in its preparation. This problem has recently been circumvented by substituting for ethyl N-hydroxycarbamate, t-butyl N-hydroxycarbamate.
O-ALLYLHYDROXYLAMINE HYDROCHLORIDE 준비 용품 및 원자재
원자재
Ethanimidic acid, N-(2-propenyloxy)-, ethyl ester
Acetamide,N-(2-propen-1-yloxy)-
N-Benzoyl-O-allylhydroxylamine
1-(아미노옥시)-2-프로펜
N-알릴록시프탈이미드
카르밤산,(2-프로페닐옥시)-,1,1-디메틸에틸에스테르(9CI)
1,3-디클로로프로펜
프탈 산
브롬화알릴
N-히드록시프탈이미드
준비 용품
O-ALLYLHYDROXYLAMINE HYDROCHLORIDE 공급 업체
글로벌( 130)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9308 | 55 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
Jiangsu Yew Pharmaceutical Co., Ltd. | +86-510-66865338 +86-189-2133-5032 @ |
junwenjiang@live.cn | CHINA | 30 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29888 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 |
sales@finerchem.com | China | 2966 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49392 | 58 |
Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 |
marketing1@neostarunited.com | China | 9105 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 |
sales@tnjchem.com | China | 34571 | 58 |
O-ALLYLHYDROXYLAMINE HYDROCHLORIDE 관련 검색:
염산 히드록실아민
O-ALLYLHYDROXYLAMINE HYDROCHLORIDE
1-(3-([(4-CHLOROPHENYL)SULFONYL]METHYL)-4-NITROPHENYL)-1-ETHANONE O-(3-CHLORO-2-PROPENYL)OXIME
1-CHLORO-4-([(CINNAMOYLOXY)IMINO]METHYL)BENZENE
5-NITRO-2-([(2,3,3-TRICHLOROALLANOYL)OXY]ETHANIMIDOYL)-1-BENZOFURAN
2,4-DICHLORO-1-(([(2,3,3-TRICHLOROALLANOYL)OXY]IMINO)METHYL)BENZENE
O1-(2,3,3-TRICHLOROACRYLOYL)-3-[3,5-DI(TRIFLUOROMETHYL)PHENYL]PROP-2-ENEHYDROXIMAMIDE
4-[(4-CHLOROANILINO)METHYLENE]-3-PHENYL-5(4H)-ISOXAZOLONE
O1-[3-(5-CHLORO-1,3-DIMETHYL-1H-PYRAZOL-4-YL)ACRYLOYL]-4-CHLOROBENZENE-1-CARBOHYDROXIMAMIDE
O-ALLYLHYDROXYLAMINE HYDROCHLORIDE HYDRATE
SPECS AH-262/36795050
O4-(2,3,3-TRICHLOROACRYLOYL)-2,6-DICHLOROPYRIDINE-4-CARBOHYDROXIMAMIDE
O1-[3-(5-CHLORO-1,3-DIMETHYL-1H-PYRAZOL-4-YL)ACRYLOYL]-4-(TERT-BUTYL)BENZENE-1-CARBOHYDROXIMAMIDE
4-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-2-(3-[4-(DIMETHYLAMINO)PHENYL]-2-PROPENYLIDENE)-5-OXO-2,5-DIHYDROISOXAZOL-2-IUM-3-OLATE
BUTTPARK 1\01-100
4-(PHENYLSULFONYL)-2-BUTANONE O-(3-CHLORO-2-PROPENYL)OXIME
N-[BIS(4-FLUOROPHENYL)METHYLENE]-N-[(2,3,3-TRICHLOROALLANOYL)OXY]AMINE
6-(2-([(3-CHLORO-2-PROPENYL)OXY]IMINO)ETHYL)-1-(3,4-DIMETHOXYPHENETHYL)-4-OXO-1,4-DIHYDRO-5-PYRIMIDINECARBONITRILE