Fmoc-L-Arg(Pbf)-OH
|
|
Fmoc-L-Arg(Pbf)-OH 속성
- 녹는점
- 132°C
- 알파
- -5.5 º (c=1,DMF)
- 밀도
- 1.37±0.1 g/cm3(Predicted)
- 저장 조건
- Store at -15°C to -25°C.
- 용해도
- DMF(난용성), DMSO (약간 용해됨), 메탄올 (약간 용해됨)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 3.83±0.21(Predicted)
- 색상
- 흰색에서 황백색까지
- optical activity
- [α]/D -5.5±1.0°, c = 1 in DMF
- BRN
- 8302671
- InChIKey
- YUMOVWGGELTYES-LJAQVGFWSA-N
- SMILES
- C(O)(=O)[C@H](CCCNC=NNS(C1=C(C)C(C)=C2OC(C)(C)CC2=C1C)(=O)=O)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
- CAS 데이터베이스
- 154445-77-9(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
Fmoc-L-Arg(Pbf)-OH C화학적 특성, 용도, 생산
화학적 성질
white powde용도
Fmoc-Arg(Pbf)-OH, is an amino acid building block used in peptide synthesis. With a growing peptide drug market the fast, reliable synthesis of peptides is of great importance.정의
Fmoc-Arg(Pbf)-OH is the standard derivative for the introduction of Arg in Fmoc SPPS. In the preparation of peptides containing both Arg and Trp, it is recommended that this derivative is used in conjunction with Fmoc-Trp(Boc)-OH. The Pbf side-chain protecting group is removed with TFA approximately 1-2 times faster than Pmc. TFA cleavage is best performed in the presence of a silane scavenger. The Pbf group of Fmoc-Arg(Pbf)-OH can be cleaved under moderate acid conditions.반응 프로필
The Pbf group of Fmoc-L-Arg(Pbf)-OH can be cleaved under moderate acid conditions. The amount of tryptophan alkylation is significantly reduced compared to other arginine side chain protecting groups, especially in the absence of scavengers. In one example reported in the literature, a peptide containing Arg(Pmc) was cleaved, and deprotected TFA resulted in 46% of the desired peptide.Fmoc-L-Arg(Pbf)-OH 준비 용품 및 원자재
원자재
준비 용품
Fmoc-L-Arg(Pbf)-OH 공급 업체
글로벌( 498)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Lanxi Xingnuo Import and Export Trading Co., Ltd | +86-15888978871 +86-13901546477 |
sales@xingnuotraders.com | China | 21 | 58 |
Chemtour Biotech Co., Ltd | +8617327281506 |
market@chemtour.com | China | 1472 | 58 |
Chengdu Baishixing Science and Technology Industry Co.,Ltd | +86-15008457246 +86-15008457246 |
yuki@cd-bsx.com | China | 53 | 58 |
Sichuan HongRi Pharma-Tech Co.,Ltd | +86-028-64841719 +8618980456393 |
daisy@enlaibio.com | China | 1369 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12456 | 58 |
Hangzhou ICH Biofarm Co., Ltd | +undefined8613073685410 |
sales@ichemie.com | China | 985 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15928 | 58 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
AB PharmaTech,LLC | 323-480-4688 |
United States | 989 | 55 |
Fmoc-L-Arg(Pbf)-OH 관련 검색:
1-[[(9H-플로렌-9-일메톡시)카보닐]옥시]-2,5-필롤리딘디온 L-(+)-아르기닌 9-플루오레닐메틸 클로로폼산 염화설퍼릴
ARGINASE
Fmoc-Asp(OtBu)-OH
Fmoc-Lys(Boc)-OH
Nalpha-Fmoc-Ndelta-trityl-L-glutamine
FMOC-b-Ala-OH
Fmoc-Phe-OH
N-Boc-N'-nitro-L-arginine
L-Fmoc-Aspartic acid alpha-tert-butyl ester
FMOC-THR(TBU)-OL
FMOC-ASU-OH
FMOC-ARG(ME,PBF)-OH
FMOC-N-METHYL-TRANEXAMIC ACID
Fmoc-L-Tyr(propargyl)-OH
Fmoc-Gly-OH