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CROMAKALIM

CROMAKALIM 구조식 이미지

카스 번호:: 94470-67-4

상품명:: CROMAKALIM

동의어(영문):: BRL-34915;CROMAKALIM;AKOS 91890;(+/-)-CROMAKALIM;Cromakalim=([+/-]-trans-6-Cyano-3,4-dihydro-2,2-;rac-(3α*,4β*)-3-Hydroxy-2,2-dimethyl-4-(2-oxopyrrolidine-1-yl)chroman-6-carbonitrile;(-trans-6-Cyano-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-3,4-dihydro-2H-benzo[b]pyran-3-ol;(3S)-3-hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-3,4-dihydrochromene-6-carbonitrile;[+/-]-TRANS-6-CYANO-3,4-DIHYDRO-2,2-DIMETHYL-4-[2-OXOPYRROLIDIN-1-YL]-2H-1-BENZOPYRAN-3-OL;(+/-)-TRANS-6-CYANO-3,4-DIHYDRO-2,2-DIMETHYL-4-(2-OXOPYRROLIDIN-1-YL)-2H-1-BENZOPYRAN-3-OL

CBNumber:: CB7771686

분자식:: C16H18N2O3

포뮬러 무게:: 286.33

MOL 파일:: 94470-67-4.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 34

CROMAKALIM 속성

녹는점: 242-244°C

저장 조건: 2-8°C

용해도: DMSO(최대 40mg/ml) 또는 에탄올(최대 10mg/ml)에 용해됩니다.

물리적 상태: 고체

물리적 상태: 단단한 모양

색상: 회백색

안정성: 제공된 대로 구매일로부터 2년 동안 안정적입니다. DMSO 또는 에탄올 용액은 -20°에서 최대 3개월 동안 보관할 수 있습니다.

안전

안전지침서	22-24/25
WGK 독일	3

CROMAKALIM C화학적 특성, 용도, 생산

개요

(±)-Cromakalim is a prototypical activator of the ATP-sensitive potassium channel, SUR2-K_ir6, that displays anti-ischemic (EC₂₅ = 8.9 μM) and cardioprotective (IC₅₀ = 0.03 μM) effects in rat hearts. (±)-Cromakalim has also been shown to relax bladder smooth muscle in vitro. It has been used to investigate potassium channel biology and as a scaffold to develop increasingly selective K⁺ channel openers with clinical relevance.

화학적 성질

White Crystalline Solid

용도

Cromakalim causes vasodilation by activation of potassim channels

생물학적 활성

Prototypical K ATP channel opener. Relaxes rabbit isolated portal vein with an IC 50 value of 21 nM . Potent, orally active and hypotensive in vivo .

CROMAKALIM 준비 용품 및 원자재

원자재

준비 용품

CROMAKALIM 공급 업체

글로벌( 34)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32344	50
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Shanghai Synchem Pharma Co., ltd	021-61984905-1 18016477331	synchempharma@aliyun.com	China	6454	55
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	sales@rrkchem.com	China	55717	58

CROMAKALIM 관련 검색:

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