벤조니트릴
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벤조니트릴 속성
- 녹는점
- -13 °C (lit.)
- 끓는 점
- 191 °C (lit.)
- 밀도
- 1.01
- 증기 밀도
- 3.6 (vs air)
- 증기압
- 1 hPa at 20 °C
- 굴절률
- n
20/D 1.528(lit.)
- 인화점
- 161 °F
- 저장 조건
- Store below +30°C.
- 용해도
- 10g/L
- 물리적 상태
- 액체
- 색상
- 무색투명~미황색
- 상대극성
- 0.333
- 냄새
- 아몬드 같은.
- 폭발한계
- 1.4-7.2%(V)
- 수용성
- 10g/L(100℃)
- 최대 파장(λmax)
- λ: 300 nm Amax: 1.0
λ: 310 nm Amax: 0.40
λ: 335 nm Amax: 0.03
λ: 360-400 nm Amax: 0.01
- Merck
- 14,1097
- BRN
- 506893
- 노출 한도
- NIOSH: IDLH 14 ppm(25 mg/m3)
- Dielectric constant
- 26.0(20℃)
- 안정성
- 안정적인. 강염기, 강산, 강산화제, 강환원제와 호환되지 않습니다. 공기에 민감합니다. 타기 쉬운.
- InChIKey
- JFDZBHWFFUWGJE-UHFFFAOYSA-N
- LogP
- 1.5 at 20℃
- CAS 데이터베이스
- 100-47-0(CAS DataBase Reference)
안전
- 위험 및 안전 성명
위험품 표기 | Xn | ||
---|---|---|---|
위험 카페고리 넘버 | 21/22-38 | ||
안전지침서 | 23 | ||
유엔번호(UN No.) | UN 2224 6.1/PG 2 | ||
WGK 독일 | 2 | ||
RTECS 번호 | DI2450000 | ||
자연 발화 온도 | 550 °C | ||
TSCA | Yes | ||
위험 등급 | 6.1 | ||
포장분류 | II | ||
HS 번호 | 29269090 | ||
유해 물질 데이터 | 100-47-0(Hazardous Substances Data) | ||
독성 | LDLo orl-rat: 720 mg/kg AMRL** TR-74-78,74 | ||
IDLA | 14 ppm (66 mg/m3) | ||
기존화학 물질 | KE-02715 |
벤조니트릴 C화학적 특성, 용도, 생산
개요
벤젠의 수소 한 개를 시아노기로 치환한 무색, 방향성 액체. 분자량 103.1, 녹는점 -13.2℃, 끓는점 191.1℃, 비중 1.0051(20℃)이다. 에틸알코올 · 벤젠 · 에테르에 녹고 물에는 약간 녹는다.용도
용제로 쓰이며 플라스틱 원료로도 이용된다.화학적 성질
Bezonitrile is a colorless, oily liquid. It has a almond odor and a bitter taste. Slightly soluble in cold water, the solubility in water at 100°C is 1%; miscible with common organic solvents. When heated to decomposition, benzonitrile emits toxic hydrogen cyanide and oxides of nitrogen (HSDB 1988).출처
Benzonitrile is reported to be found in natural cocoa aroma), in milk products, roasted filberts and peanuts and cooked trassi . Benzonitrile also has been detected in the thermal decomposition products of flexible polyurethane foam.용도
The most important commercial use for benzonitrile is the synthesis of benzoguanamine, which is a derivative of melamine and is used in protective coatings and molding resins. It is used intermediate for rubber chemicals; solvent for nitrile rubber, specialty lacquers, and many resins and polymers, and for many anhydrous metallic salts.주요 응용
Benzonitrile is a widely utilized as a solvent and an intermediate in industries making drugs, perfumes, dyes, rubber, textiles, resins and specialty lacquers. It finds application as a versatile precursor for many derivatives. It coordinates with transition metal to form complexes which act as synthetic intermediates.제조 방법
Benzonitrile can be prepared by following methods:1) on a small scale by the dehydration in an inert solvent with phosphorus oxychloride or benzenesulfonyl chloride and an organic amine.
2) from benzoic acid by heating with lead thiocyanate.
3) by heating sodium benzenesulfonate with sodium cyanide.
4) by adding benzenediazonium chloride solution to a hot aq sodium cyanide solution containing cupric sulfate and distilling by ammoxidation of toluene.
Benzonitrile can also be produced in high yield by the vapor-phase catalytic ammoxidation of toluene.
정의
ChEBI: Benzonitrile is a nitrile that is hydrogen cyanide in which the hydrogen has been replaced by a phenyl group. It is a member of benzenes and a nitrile.공기와 물의 반응
Slightly soluble in water.반응 프로필
The cyano group can be readily hydrolyzed in the presence of mineral acids to produce stable, moderately toxic benzoic acid . When heated to decomposition, Benzonitrile emits highly toxic fumes of nitrogen oxides and hydrogen cyanide [Sax, 9th ed., 1996, p. 353].위험도
High toxicity; absorbed by skin.건강위험
Benzonitrile may enter the human body by ingestion, absorption through the skin, or inhalation. The earliest symptoms of cyano compound intoxication may be weakness, headaches, confusion, and occasionally nausea and vomiting. The respiratory rate and depth will usually be increased at the beginning and at later stages become slow and gasping. Blood pressure is usually normal, especially in the mild or moderately severe cases, although the pulse rate is usually more rapid than normal.화재위험
Special Hazards of Combustion Products: Toxic hydrogen cyanide and oxides of nitrogen may form in fire.공업 용도
Benzonitrile is used as an intermediate for rubber chemicals and as a solvent for nitrile rubber, specialty lacquers, many resins, polymers and for many anhydrous metallic salts (HSDB 1988; Hawley 1981). It is principally used as an intermediate for benzoguanamine (HSDB 1988). It is also used as an additive in nickel-plating baths, separating naphthalene and alkylnaphthalenes from non-aromatics by azetropic distillation; as jet-fuel additive; in cotton bleaching baths; as a drying additive for acrylic fibers; and in the removal of titanium tetrachloride and vanadium oxychloride from silicon tetrachloride (HSDB 1988; Smiley 1981). Benzonitrile is also used in perfumes at a maximum level of 0.2% in the final product (Opdyke 1979).Safety Profile
Poison by intraperitoneal andsubcutaneous routes. Moderately toxic by ingestion,inhalation, and skin contact. A skinirritant. Combustible liquid. When heated todecomposition it emits toxic fumes of CN- and NOx.신진 대사
Benzonitrile is mainly hydroxylated in vivo to cyanophenols, a small amount being hydrolysed to benzoic acid (Williams 1959). Benzonitrile also forms 6>-hydroxybenzonitrile, m-hydroxybenzonitrile, and /p-hydroxybenzonitrile in rabbits (HSDB 1988). In rabbit, 50% of a dose of 150 mg/kg was converted to conjugated cyanophenols and 10% of the benzonitrile fed was excreted as benzoic acid. Hydrogen cyanide is not a metabolite of benzonitrile (Williams 1959) and cyanide was not found to be formed by benzonitrile either in vivo or in vitro (Tanii and Hashimoto 1984). The in vivo microsomal hydroxylation of specifically deuterated benzonitrile in the rat yielded mainly 4-hydroxybenzonitrile with 41% retention of deuterium (Daly et al 1968).운송 방법
UN2224 Benzonitrile, Hazard Class: 6.1; Labels: 6.1—Poisonous materials.Purification Methods
Dry benzonitrile with CaSO4, CaCl2, MgSO4 or K2CO3, and distil it from P2O5 in an all-glass apparatus, under reduced pressure (b 69o/10mm), collecting the middle fraction. Distillation from CaH2 causes some decomposition of benzonitrile. Isonitriles can be removed by preliminary treatment with conc HCl until the odour of isonitrile (carbylamine) has gone, followed by preliminary drying with K2CO3. (This treatment also removes amines.) Steam distil (to remove small quantities of carbylamine). The distillate is extracted into ether, washed with dilute Na2CO3, dried overnight with CaCl2, and the ether is removed by evaporation. The residue is distilled at 40mm (b 96o) [Kice et al. J Am Chem Soc 82 834 1960]. Conductivity grade benzonitrile (specific conductance 2 x 10-8 mho) is obtained by treatment with anhydrous AlCl3, followed by rapid distillation at 40-50o under vacuum. After washing with alkali and drying with CaCl2, the distillate is redistilled in a vacuum several times at 35o before fractionally crystallising several times by partial freezing. It is dried over finely divided activated alumina from which it is withdrawn when required [Van Dyke & Harrison J Am Chem Soc 73 402 1951]. [Beilstein 9 IV 892.]비 호환성
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. They are incompatible Benzonitrile with acids; mixing nitriles with strong oxidizing acids can lead to extremely violent reactions.폐기물 처리
(1) Mix with calcium hypochlorite and flush to sewer with water or (2) incinerate.벤조니트릴 준비 용품 및 원자재
원자재
준비 용품
Ethyl N-(diphenylmethylene)glycinate
벤조쿠아나민
CYCLOPROTHRIN
Alclometasone Dipropionate
3-Nitrobenzonitrile
3-BENZOYL PROPIOPHENONE
4-CHLORO-2,5-DIPHENYLTHIENO[2,3-D]PYRIMIDINE
1,4-Bis(4-cyanostyryl)benzene
3,5-다이브로모-4-하이드록시벤조나이트릴 및 그 염류
라놀린
3,4,5-트리메톡시벤즈알데히드
클로로타로닐
4-tert-Butylbenzylamine
디클로로 비스 (벤조 니트릴) 팔라듐 (II)
디미듐 브로마이드
Azosemide
2,6-DIMETHOXYBENZONITRILE
Sulphur Blue 7
1,3,5-Triazine, 2-phenyl- (9CI)
METHYL(5-MERCAPTO-1H-BENZIMIDAZOL-2-YL)CARBAMATE
Prazosin
벤자마이드 옥심
Bunazosin hydrochloride
아미트라즈
5-페닐-1H-테트라졸
디페닐메타니민
벤조니트릴 공급 업체
글로벌( 387)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12456 | 58 |
Wuhan Biet Co., Ltd. | +8617320528784 |
min@biet.com.cn | China | 41 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 |
info@tnjchem.com | China | 2989 | 55 |
career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8823 | 58 |
Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 |
sales@amoychem.com | China | 6387 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |