4-메톡시페놀
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4-메톡시페놀 속성
- 녹는점
- 56 °C
- 끓는 점
- 243 °C(lit.)
- 밀도
- 1,55 g/cm3
- 증기 밀도
- 4.3 (vs air)
- 증기압
- <0.01 mm Hg ( 20 °C)
- 굴절률
- 1.5286 (estimate)
- 인화점
- >230 °F
- 저장 조건
- Store below +30°C.
- 용해도
- 아세톤, 에틸 아세테이트, 에탄올, 에테르, 벤젠 및 사염화탄소에 용해됩니다.
- 물리적 상태
- 액체
- 산도 계수 (pKa)
- 10.21(at 25℃)
- 색상
- 무색~담황색 투명
- 수소이온지수(pH)
- 5.1 (30g/l, H2O, 20℃)
- 냄새
- 1.00?%?in?디프로필렌 글리콜에서. 페놀성
- Odor Threshold
- 0.0027ppm
- 수용성
- 40g/L(25℃)
- BRN
- 507924
- 노출 한도
- ACGIH: TWA 5 mg/m3
NIOSH: TWA 5 mg/m3
- 안정성
- 안정적인. 타기 쉬운. 할로겐, 산화제와 호환되지 않습니다.
- InChIKey
- NWVVVBRKAWDGAB-UHFFFAOYSA-N
- LogP
- 1.3 at 20℃
- CAS 데이터베이스
- 150-76-5(CAS DataBase Reference)
- NIST
- Mequinol(150-76-5)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 22-36-43 | ||
| 안전지침서 | 24/25-26-37/39-46 | ||
| WGK 독일 | 1 | ||
| RTECS 번호 | SL7700000 | ||
| 자연 발화 온도 | 789 °F | ||
| TSCA | Yes | ||
| HS 번호 | 29095090 | ||
| 유해 물질 데이터 | 150-76-5(Hazardous Substances Data) | ||
| 독성 | LD50 orally in Rabbit: 1600 mg/kg | ||
| 기존화학 물질 | KE-23353 |
4-메톡시페놀 C화학적 특성, 용도, 생산
화학적 성질
4-Methoxyphenol is a colorless to white, waxy solid with an odor of caramel and phenol. It is a combustible solid. It is used as an inhibitor for acrylic monomers and as a stabilizer for chlorinated hydrocarbons, ethyl cellulose, and UV inhibitors.Synthesis
4-Methoxyphenol was synthesised according to Oxidation with H2O2 and a Diselenide catalyst.p-Anisaldehyde (50 mmol) is dissolved in CH2Cl2 (100mL) and (o-NO2PhSe)2 (2 mmol) and 30% H2O2 (13mL, 128 mmol) are added. The mixture is stirred magnetically at room temperature (water bath) for 30 minutes. Insoluble catalyst is removed by filtration and washed with CH2Cl2 (20mL) and water (20mL). It can be reused after drying. To the filtrate and washings, water (100mL) is added, and the layers are separated after shaking. The organic layer is washed subsequently with 10% NaHSO3 (100mL), 10% Na2CO3 (100mL), water (100mL) and dried over Na2SO4. 4-methoxyphenol is obtained by alkaline hydrolysis of the residue. Yield: 93%.
Indications
Mequinol (4-hydroxyanisole) is a substrate of the enzyme tyrosinase and acts as a competitive inhibitor of melanogenesis.화학 반응
4-methoxyphenol(4-MP) may be used in the synthesis of butylated hydroxy anisoles via alkylation with methyl tert-butyl ether over a non-zeolitic solid acidic catalyst. This process is eco-friendly when compared to the Friedel-Crafts alkylation reaction. 4-MP may also react with aqueous nitrous acid to form 2-nitro-4-methoxyphenol and benzoquinone in varying ratios depending on the reaction conditions. 4-MP can be used as a building block in designing β-cyclodextrin 4-methoxyphenol conjugates that can be potential ligands for drug complexation.일반 설명
Pink crystals or white waxy solid.공기와 물의 반응
Sensitive to moisture. Water soluble.반응 프로필
4-Methoxyphenol can react with oxidizing materials.위험도
Eye irritant and skin damage.건강위험
4-Methoxyphenol is expected to cause liver and renal toxicity with narcosis, but only at high levels of exposure.화재위험
CombustibleSafety Profile
Poison by intraperitoneal route. A skin irritant. When heated to decomposition it emits acrid smoke and fumes. See also ETHERS.운송 방법
UN3335 Aviation regulated solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required.Purification Methods
Crystallise 4-methoxyphenol from *benzene, pet ether or H2O, and dry it under vacuum over P2O5 at room temperature. Sublime it in vacuo. [Wolfenden et al. J Am Chem Soc 109 463 1987, Beilstein 6 IV 5717.]4-메톡시페놀 준비 용품 및 원자재
원자재
Methanol solution
에틸알코올
하이드로퀴논
Benzene
메틸알콜
퀴논
황산
Silane, (1,1-dimethylethyl)(4-methoxyphenoxy)dimethyl-
4-Chloroanisole
4-ALLYLOXYANISOLE
4-Methoxyphenylboronic acid
p-브로모아니졸
준비 용품
5-메톡시살릴리산
N-이소프로필아크릴아마이드
5-Methoxybenzofuran
Disperse Red 146
5-Methoxybenzofuran-2-carboxylic acid
부틸레이티드 하이드록시 아니솔
6-METHOXY-2-OXO-2H-CHROMENE-3-CARBOXYLIC ACID
N-NONYL ACRYLATE
2-METHOXY-5-(2'-ETHYLHEXYLOXY)BENZENE-1&
2-Hydroxy-5-methoxybenzaldehyde
5-METHOXYBENZOFURAN-2-CARBOXYLIC ACID, ETHYL ESTER
4-methoxyphenyl benzoate
3-Bromo-2,5-dimethoxyaniline
2,3-EPOXYPROPYL-4-METHOXYPHENYL ETHER
Disperse Red 146
6-Methoxy-2,2-diMethyl-2h-chroMene
4-메톡시페놀 공급 업체
글로벌( 870)공급 업체
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info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
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