Arsphenamine

Arsphenamine 구조식 이미지
카스 번호:
139-93-5
상품명:
Arsphenamine
동의어(영문):
SALVARSAN;arsphenamine;3,3'-Diamino-4,4'-Dihydroxyarsenobenzene;4,4-ARSENOBIS(2-AMINOPHENOL)DIHYDROCHLORIDE;6,6'-dihydroxy-3,3'-diarsene-1,2-diyldianilinium dichloride;2-amino-4-(3-amino-4-hydroxyphenyl)arsanylidenearsanylphenol
CBNumber:
CB7933479
분자식:
C12H14As2Cl2N2O2
포뮬러 무게:
439.00096
MOL 파일:
139-93-5.mol

Arsphenamine 속성

녹는점
190°C (rough estimate)
물리적 상태
고체
물리적 상태
단단한 모양

안전

독성 LD100 i.v. in rats: 140 mg/kg (Schamberg)

Arsphenamine C화학적 특성, 용도, 생산

Pharmaceutical Applications

Salvarsan was a synthetic arsenic-based drug discovered in 1909 by Ehrlich and his team. In 1910, Ehrlich introduced Salvarsan (3-amino-4-hydroxyphenylarsenic), also known as arsphenamine or compound 606, to the market as a cure for syphilis caused by the bacterium Treponema pallidum.
Eventually, compound 606 was synthesised and introduced as an agent against syphilis. The compound was later marketed as Salvarsan, receiving its name from the Latin word salvare , which means to preserve, to heal. In 1909 and 1910, the first human tests on patients with syphilis and relapsing fever were extremely successful, and Salvarsan was marketed from 1910. For the first time, an infectious and fatal disease in humans could be treated with a man-made molecule, and Salvarsan brought Ehrlich world-wide fame. Generally, the use of arsenic-based drugs has ceased, especially as a result of the development of Penicillin. Nevertheless, Melarsoprol and an arsenic-based drug closely related to Atoxyl are licensed to treat sleeping sickness.

Arsphenamine 준비 용품 및 원자재

원자재

준비 용품


Arsphenamine 공급 업체

글로벌( 4)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Portail Substances Chimiques --
webmestre-substances@ineris.fr France 6027 58
Molekula Ltd --
info@molekula.com United Kingdom 4061 50
HONEST JOY HOLDINGS LIMITED --
sales@honestjoy.cn United States 6702 54
Yick-Vic Chemicals & Pharmaceuticals (HK) Ltd --
sales@yickvic.com China 6214 58

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