Isochlorogenic acid A

Isochlorogenic acid A 구조식 이미지
카스 번호:
2450-53-5
상품명:
Isochlorogenic acid A
동의어(영문):
3,5-Dicaffeoylquinic acid;3,5-CQA;CJ 4-16-4;Isochloric acid A;Isochlorogenic acid A;3,5-Dicaffeylquinic acid;ISOCHLOROGENIC ACID A(SH);3',5'-Isochlorogenic acid A;Quinic acid 3,5-di-O-caffeate;Isochlorogenic acid A, froM Lonicera japonica
CBNumber:
CB81040694
분자식:
C25H24O12
포뮬러 무게:
516.46
MOL 파일:
2450-53-5.mol
MSDS 파일:
SDS

Isochlorogenic acid A 속성

녹는점
>175°C (dec.)
끓는 점
826.2±65.0 °C(Predicted)
밀도
1?+-.0.1 g/cm3(Predicted)
저장 조건
-20°C
용해도
DMSO(약간 용해됨), 메탄올(약간 용해됨)
산도 계수 (pKa)
3.54±0.50(Predicted)
물리적 상태
황백색에서 노란색/갈색의 결정성 고체.
색상
황백색에서 연한 노란색
안정성
흡습성
InChIKey
KRZBCHWVBQOTNZ-PSEXTPKNSA-N

안전

안전지침서 24/25
WGK 독일 3
RTECS 번호 GU8403966
HS 번호 29189900

Isochlorogenic acid A C화학적 특성, 용도, 생산

개요

3,5-Dicaffeoylquinic acid (3,5-DCQA) is a natural phenolic compound that has been found in L. japonica, I. kaushue, and other plants. It has antioxidant, anti-inflammatory, and antiviral biological activities. 3,5-DCQA scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in a cell-free assay (IC50 = 71.8 μM) and inhibits superoxide production in human neutrophils activated by N-formyl-Met-Leu-Phe (fMLF) and cytochalasin B (IC50 = 1.92 μM). It inhibits HIV-1 integrase 3''-end processing, strand transfer, and disintegration in a cell-free assay (IC50s = 0.33, 0.34, and 0.66 μg/ml, respectively) and inhibits HIV-1-induced cytotoxicity in MT-2 cells (ED50 = 1 μg/ml). In vivo, 3,5-DCQA (25 mg/kg) protects mice from acute lung injury induced by LPS and decreases neutrophil count in bronchoalveolar lavage fluid (BALF).

용도

Isochlorogenic Acid A is a phenolic compound shown to provide protection against oxidative stress cells. DNA protective agent.

Isochlorogenic acid A 준비 용품 및 원자재

원자재

준비 용품


Isochlorogenic acid A 공급 업체

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CONIER CHEM AND PHARMA LIMITED
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sales@conier.com China 49390 58

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