Ecdysone

Ecdysone 구조식 이미지
카스 번호:
3604-87-3
상품명:
Ecdysone
동의어(영문):
ECDYSONE;A-ECDYSONE;Ecdyterone;α-Ecdysone;ALPHA-ECDYSON;ALPHA-ECYSONE;ALPHA-ECDYSONE;ECDYSONE, ALPHA-;ALPHA-ECDYSTERONE;α-Ecdysone ( >90%)
CBNumber:
CB8113524
분자식:
C27H44O6
포뮬러 무게:
464.63
MOL 파일:
3604-87-3.mol

Ecdysone 속성

녹는점
242°C
알파
20578 +62°
끓는 점
488.1°C (rough estimate)
밀도
1.0493 (rough estimate)
굴절률
1.4482 (estimate)
저장 조건
2-8°C
용해도
메탄올(아주 약간 가열)
산도 계수 (pKa)
14.07±0.70(Predicted)
물리적 상태
고체
물리적 상태
단단한 모양
색상
흰색에서 황백색까지
Merck
13,3525
BRN
2422986
InChIKey
UPEZCKBFRMILAV-JMZLNJERSA-N
SMILES
[C@H]1(C[C@@]2([C@](C)(C[C@@H]1O)[C@]1([H])C([C@]3([C@@](CC1)(C)[C@@H]([C@H](C)[C@@H](CCC(C)(C)O)O)CC3)O)=CC2=O)[H])O
LogP
0.870 (est)
CAS 데이터베이스
3604-87-3(CAS DataBase Reference)

안전

안전지침서 22-24/25
WGK 독일 3
RTECS 번호 FZ8170000
F 고인화성물질 10

Ecdysone C화학적 특성, 용도, 생산

개요

?Ecdysterone, also known as ecdysone or β-ecdysone, is a hormone that regulates the growth and development of insects. In 1954, Butenandt et al. isolated 250mg of the initial insect metamorphic active substance, ecdysone, from 500kg of silkworm pupae. Since then, various similar substances have been isolated from many plants. It has been found that ecdysteroids are not only more abundant in the plant kingdom compared to the animal kingdom, but also widely distributed and abundant in resources. Examples of ferns that contain ecdysteroids include Chinese cornbind, Sichuan cornbind, mulberry leaves, Dectenium heterocarpon, water plantain, Ginkgo biloba, yew, Thelypteris palustris, and Cyrtomium falcatum, among others.

용도

α-Ecdysone is a steroidal prohormone.

신진 대사 경로

When white mice are administered 3H-ecdyson, (2b,3b,14a,22(R),25-pentahydroxy-5b-cholest-7-ene-6- one) by injection intraperitoneally, ecdysone is metabolized via hydroxylation at C14, followed by reduction of ring B into the 6a-hydroxy derivative and epimerization at C3.

Purification Methods

Recrystallise -ecdyson from tetrahydrofuran/pet ether and from H2O as a hydrate. It has been purified by chromatogaphy on Al2O3 and elution with EtOAc/MeOH. It has max at 242nm ( 12,400). Its acetate has m 214-216o from EtOAc/pet ether, and the 2,4-dinitrophenylhydrazone has m 170-175o(dec) from EtOAc. [Karlson & Hoffmeister Justus Liebigs Ann Chem 662 1 1963, Karlson Pure Appl Chem 14 75 1967, Beilstein 8 IV 3613.]

Ecdysone 준비 용품 및 원자재

원자재

준비 용품


Ecdysone 공급 업체

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