파니투무맙

파니투무맙
파니투무맙 구조식 이미지
카스 번호:
339177-26-3
한글명:
파니투무맙
동의어(한글):
파니투무맙
상품명:
Panitumumab
동의어(영문):
Abenix;Abx-egf;Vectibix;Panitumumab;Abx-egf mab;Unii-6A901E312a;Panitumumab USP/EP/BP;Panitumumab (anti-EGFR);Research Grade Panitumumab(DHB86903);Research Grade Pintumomab (DHJ57401)
CBNumber:
CB81216039
분자식:
포뮬러 무게:
0
MOL 파일:
Mol file

파니투무맙 속성

저장 조건
Store at -20°C
물리적 상태
Liquid
색상
Colorless to light yellow

안전

파니투무맙 C화학적 특성, 용도, 생산

개요

Panitumumab is a recombinant, fully human IgG2 kappa monoclonal antibody that is highly selective for the epidermal growth factor receptor (EGFR), and it is indicated for the treatment of EGFR-expressing, metastatic colorectal carcinoma (mCRC) with disease progression on or following fluoropyrimidine-, oxaliplatin-, and irinotecan-containing chemotherapy regimens. Overexpression of EGFR is detected in many human cancers, including those of the colon and rectum. Panitumumab blocks the binding of ligands such as epidermal growth factor (EGF) and transforming growth factor (TGF-a) to various EGFR-expressing cell lines, which results in inhibition of EGF-dependent tumor cell activation, induction of apoptosis, and decreased pro-inflammatory cytokine and vascular growth factor production. In vitro, panitumumab binds EGFR with high affinity (KD ? 50pM; IC50 ? 3 nM) in human cervical epidermal cell line A-431. .

용도

Antineoplastic.

파니투무맙 준비 용품 및 원자재

원자재

준비 용품


파니투무맙 공급 업체

글로벌( 60)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Biochempartner
0086-13720134139
candy@biochempartner.com CHINA 967 58
Hubei xin bonus chemical co. LTD
86-13657291602
linda@hubeijusheng.com CHINA 22968 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 24099 58
Hefei Hirisun Pharmatech Co., Ltd
+8615056975894
shawn@hirisunpharm.com CHINA 9923 58
TargetMol Chemicals Inc.
+1-781-999-5354
support@targetmol.com United States 19973 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525
masar@topule.com China 8474 58
LEAPCHEM CO., LTD.
+86-852-30606658
market18@leapchem.com China 43348 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 57511 58
Wuhan Chemstan Biotechnology Co., Ltd. 027-65317797 15926423062
422450190@qq.com China 10351 58
LGM Pharma 1-(800)-881-8210
inquiries@lgmpharma.com United States 2127 70

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