CGS 21680

CGS 21680 구조식 이미지
카스 번호:
120225-54-9
상품명:
CGS 21680
동의어(영문):
C061282;Cgs-21680c;(124182-57-6) cgs 21680;2-(4-(2-Carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine;2-[[2-[4-(2-Carboxyethyl)phenyl]ethyl]amino]-5'-ethylamino-5'-oxo-5'-deoxyadenosine;2-[[2-[4-(3-Hydroxy-3-oxopropyl)phenyl]ethyl]amino]-5'-deoxy-5'-oxo-5'-(ethylamino)adenosine;3-(4-(2-((6-Amino-9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxytetrahydro-furan-2-yl)-9H-p;4-[2-[[6-Amino-9-(N-ethyl-b-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid;4-[2-[[6-Amino-9-(N-ethyl-beta-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid;Benzenepropanoic acid, 4-[2-[[6-amino-9-(N-ethyl-β-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]-
CBNumber:
CB81369564
분자식:
C23H29N7O6
포뮬러 무게:
499.52
MOL 파일:
120225-54-9.mol

CGS 21680 속성

밀도
1.60
저장 조건
under inert gas (nitrogen or Argon) at 2–8 °C
용해도
DMSO에 최대 3.4mg/mL, 45%(w/v) 수성 2-하이드록시프로필-β-사이클로덱스트린에 20mg/mL까지 용해됩니다.
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
4.67±0.10(Predicted)

안전

CGS 21680 C화학적 특성, 용도, 생산

용도

CGS 21680 hydrochloride is currently used in research in studying neuronal transmission, also in respiration. CGS 21680 is commonly used to study the actions of the adenosine A2A receptor in cells and tissues. CGS 21680 HCl is an adenosine A2 receptor agonist with IC50 of 22 nM, exhibits 140-fold over A1 receptor. CGS 21680C effectively increases coronary flow with an ED25 value of 1.8 nM. In hippocampal slices, CGS 21680 apis weak agonist on pre- and postsynaptic measures of electrophysiologicaJ activity.

정의

ChEBI: A derivative of adenosine in which the 5'-hydroxymethyl group is replaced by N-ethylcarboxamido and the hydrogen at position 2 on the adenine is replaced by a 4-(2-carboxyethyl)phenethylamino group.

CGS 21680 준비 용품 및 원자재

원자재

준비 용품


CGS 21680 공급 업체

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