Nefazodone hydrochloride
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Nefazodone hydrochloride 속성
- 녹는점
- 186-188°C
- 저장 조건
- Inert atmosphere,Room Temperature
- 용해도
- DMSO: ~11mg/mL( 60 °C)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 하얀색
- 최대 파장(λmax)
- 248nm(MeOH)(lit.)
- Merck
- 14,6438
- CAS 데이터베이스
- 82752-99-6(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
안전지침서 | 22-24/25 | ||
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유엔번호(UN No.) | UN1230 - class 3 - PG 2 - Methanol, solution | ||
WGK 독일 | 3 | ||
RTECS 번호 | XZ5483009 | ||
HS 번호 | 2933595960 |
그림문자(GHS): | ||||||||||||||||||||||||||||||||||||
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신호 어: | Warning | |||||||||||||||||||||||||||||||||||
유해·위험 문구: |
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예방조치문구: |
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Nefazodone hydrochloride C화학적 특성, 용도, 생산
개요
Nefazodone, a second generation trazodone type antidepressant, was launched in Canada. Nefazodone acts as both a potent 5-HT2 receptor antagonist and as a serotonin (5-HT) reuptake inhibitor. This combination effect appears to enhance 5-HTIA-mediated neurotransmission. Distinct from the first generation agents such as tricyclic antidepressants, nefazodone has very selective serotonergic effects with negligible affinity for cholinergic and histamine receptors, and low affinity for a1 -adrenergic receptors. Therefore, it has a superior toxicity profile that does not produce agitation, insomnia, and lacks cardiac side effects.화학적 성질
White Solid용도
A selective serotonin 5-HT2 receptor antagonist. A novel antidepressant that shows no cardiac toxicity or anticholinergic activity common with tricyclic antidepressants.일반 설명
Nefazodone, formerly sold under the brand names Serzone, Dutonin, and Nefadar, is an antidepressant that has been discontinued due to the incidence of severe liver damage. This certified Snap-N-Spike; solution is suitable for use as a starting material in calibrators and controls for numerous GC/MS or LC/MS applications in forensic analysis, clinical toxicology and urine drug testing.생물학적 활성
Serotonin 5-HT 2A receptor antagonist (K i = 5.8 nM) and inhibitor of serotonin and noradrenalin uptake (IC 50 values are 290 and 300 nM respectively). Displays no activity at 5-HT 1B and 5-HT 1D receptors. Active in models predictive of antidepressant potential.Nefazodone hydrochloride 준비 용품 및 원자재
원자재
준비 용품
Nefazodone hydrochloride 공급 업체
글로벌( 204)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21695 | 55 |
career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 47465 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-81148696 +8615536356810 |
1047@dideu.com | China | 3730 | 58 |
AFINE CHEMICALS LIMITED | 0571-85134551 |
info@afinechem.com | CHINA | 15377 | 58 |
Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 |
dominicguo@gk-bio.com | CHINA | 9427 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 |
info@dycnchem.com | CHINA | 52867 | 58 |
Hong Kong Excellence Biotechnology Co., Ltd. | +86-86-18838029171 +8618126314766 |
ada@sh-teruiop.com | China | 892 | 58 |
Nefazodone hydrochloride 관련 검색:
푸라졸리돈 나파졸린 1-(4-클로로페녹시)-3,3-다이메틸-1-(1H-1,2,4-트리아졸-1-일)-2- 부타논 트라조돈
Naphazoline hydrochloride
Topotecan hydrochloride
Nefazodone Related Compound A,Nefazodone Related Compound A
Nefazodone Related Compound B,Nefazodone Related Compound B
NEFAZODONE,Nefazodone base,Nefazodone (base and/or unspecified salts),NEFAZODONE,Nefazodone base,Nefazodone (base and/or unspecified salts)
1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine hydrochloride
HYDROXY NEFAZODONE HCL,HYDROXY NEFAZODONE HCL
Nefazodone hydrochloride
NEFAZODONE , TRAZODONE,NEFAZODONE , TRAZODONE
5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazole-3-one (intermediate of nefazodone hcl)
HYDROXY NEFAZODONE-D5 HCL,HYDROXY NEFAZODONE-D5 HCL