ChemicalBook
Chinese English Japanese Germany Korea

규산 마그네슘

규산 마그네슘
규산 마그네슘 구조식 이미지
카스 번호:
14987-04-3
한글명:
규산 마그네슘
동의어(한글):
규산마그네슘;규산마그네슘(MAGNESIUMSILICATE);마그네슘트라이실리케이트
상품명:
Magnesium trisilicate
동의어(영문):
petimin;magnosil;meerschaum;dicarbocalm;Trisilicalm;parasepiolite;MAGNESII TRISILICAS;Magnesium trisilicat;MAGNESIUM TRISILICATE;Magnesiumsiliconoxide
CBNumber:
CB8205317
분자식:
Mg2O8Si3
포뮬러 무게:
260.86
MOL 파일:
14987-04-3.mol

규산 마그네슘 속성

RTECS 번호
IN6620000
용해도
Practically insoluble in water and in ethanol (96 per cent).
물리적 상태
Powder
색상
White
수용성
insoluble H2O, EtOH [CRC10]
Merck
14,5687
CAS 데이터베이스
14987-04-3(CAS DataBase Reference)

안전

WGK 독일 3
TSCA Yes

규산 마그네슘 C화학적 특성, 용도, 생산

화학적 성질

White or almost white powder.

화학적 성질

The USP 32 describes magnesium trisilicate as a compound of magnesium oxide and silicon dioxide with varying proportions of water. It contains not less than 20.0% of magnesium oxide and not less than 45.0% of silicon dioxide. The PhEur 6.0 similarly describes magnesium trisilicate as having a variable composition corresponding to the approximate formula Mg2Si3O8·xH2O. It contains not less than 29.0% of magnesium oxide and not less than the equivalent of 65.0% of silicon dioxide, both calculated with reference to the ignited substance.
Magnesium trisilicate occurs as an odorless and tasteless, fine, white-colored powder that is free from grittiness.

용도

Industrial odor absorbent, decolorizing agent, antioxidant, medicine (antacid).

정의

USP specifies not less than 20% magnesium oxide and 45% SiO2, similar to the FCC requirements for magnesium silicate. See talc.

생산 방법

Magnesium trisilicate may be prepared from sodium silicate and magnesium sulfate. It also occurs in nature as the minerals meerschaum, parasepiolite, and sepiolite.

상표명

Trimax (Sterling Winthrop).

Pharmaceutical Applications

Magnesium trisilicate is used in oral pharmaceutical formulations and food products as a glidant. It is also used therapeutically as an antacid, and also for the treatment of ciprofloxacin overdose or toxicity.

Pharmaceutical Applications

Magnesium trisilicate (Mg2Si3O8) can be used in antacid preparations especially in the treatment of peptic ulcers. The mode of action includes the increase of the pH of the gastric fluid together with the formation of a colloidal silica precipitate,which forms a protection for theGImucosa. Magnesium trisilicate reduces the absorption of iron products, certain antibiotics (such as Nitrofurantoin) or antimalarial drugs (such as Proguanil).

Safety

Magnesium trisilicate is used in oral pharmaceutical formulations and is generally regarded as an essentially nontoxic and nonirritant material.
When administered orally, magnesium trisilicate is neutralized in the stomach to form magnesium chloride and silicon dioxide; some magnesium may be absorbed. Caution should be used when concentrations greater than 50 mEq of magnesium are given daily to persons with impaired renal function, owing to the risk of hypermagnesemia.
Therapeutically, up to about 2 g of magnesium trisilicate may be taken daily as an antacid. Reported adverse effects include the potential for osmotic diarrhea in the elderly using antacids containing magnesium trisilicate;and the potential for the formation of bladder and renal calculi following the long-term use of magnesium trisilicate as an antacid.

저장

Magnesium trisilicate is stable if stored in a well-closed container in a cool, dry place.

비 호환성

Magnesium trisilicate, when taken with drugs such as mebeverine hydrochloride,proguanil,norfloxacin,sucralfate, and tetracycline, may cause a reduction in bioavailability via binding or chelation. The dissolution rate of folic acid, erythromycin stearate,paracetamol, and chloroquine phosphate may be retarded by adsorption onto magnesium trisilicate. Antimicrobial preservatives, such as the parabens, may be inactivated by the addition of magnesium trisilicate.
Magnesium trisilicate is also readily decomposed by mineral acids.

Regulatory Status

GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (oral tablets). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

규산 마그네슘 준비 용품 및 원자재

원자재

준비 용품


규산 마그네슘 공급 업체

글로벌( 184)공급 업체
공급자 전화 팩스 이메일 국가 제품 수 이점
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3194 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21676 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30001 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23980 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 sales@jushengtech.com CHINA 28236 58
Xiamen AmoyChem Co., Ltd
+86 592-605 1114
sales@amoychem.com CHINA 6372 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 sales@guangaobio.com CHINA 23049 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 35440 58

Copyright 2019 © ChemicalBook. All rights reserved