L-Homophe-OH
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L-Homophe-OH 속성
- 녹는점
- >300 °C(lit.)
- 알파
- 45 º (C=1, 3N HCl 19 ºC)
- 끓는 점
- 311.75°C (rough estimate)
- 밀도
- 1.1248 (rough estimate)
- 굴절률
- 44 ° (C=1, 3mol/L HCl)
- 저장 조건
- Keep in dark place,Inert atmosphere,Room temperature
- 용해도
- 묽은 수성 산에 용해됩니다.
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 2.32±0.10(Predicted)
- 색상
- 흰색에서 황백색까지
- InChI
- InChI=1/C10H13NO2/c11-9(10(12)13)7-6-8-4-2-1-3-5-8/h1-5,9H,6-7,11H2,(H,12,13)/t9-/s3
- InChIKey
- JTTHKOPSMAVJFE-VIFPVBQESA-N
- SMILES
- C(O)(=O)[C@H](CCC1=CC=CC=C1)N |&1:3,r|
- CAS 데이터베이스
- 943-73-7(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
L-Homophe-OH C화학적 특성, 용도, 생산
화학적 성질
White Solid주요 응용
L-homophenylalanine is used almost exclusively as single stereoisomer in pharmaceutical drug production. L-homophenylalanine as a common building block, due to the presence of L-homophenylalanine moiety as the central pharmacophore unit. L-homophenylalanine is also an important chiral intermediate to synthesize a variety of novel pharmaceuticals including β-lactam antibiotics, acetylcholinesterase inhibitor and neutral endopeptidace (NEP) inhibitor which retained their status as major contributors to human health preservation. L-homophenylalanine acts as a precursor for the synthesis of NEP inhibitors, which complements the effects of ACE inhibitors when used simultaneously, potentiates the outcome in the management of hypertension and congestive heart failure[1].용도
L-Homophenylalanine is used as a precursor in the pharmaceutical industry for the production of angiotensin-converting enzyme (ACE) and R-(-)-Homophenylalanin-ethylester. It is also involved in the synthesis of NEPA [(S,S)-N-(1-Ethoxycarbonyl-3-phenylpropyl)alanine], which is a key intermediate to prepare the ACE-inhibitors: enalapril, delapril, quinapril and ramipril. It acts as an anti-tumor reagent.정의
ChEBI: A non-proteinogenic L-alpha-amino acid that is an analogue of L-phenylalanine having a 2-phenylethyl rather than a benzyl side-chain.L-Homophe-OH 준비 용품 및 원자재
원자재
4-Morpholinecarboxylic acid, 2-oxo-3-(2-oxo-2-phenylethyl)-5,6-diphenyl-, phenylmethyl ester, (3S,5S,6R)-
2-acetamido-4-phenyl-butanoic acid
D-Homophenylalanine
(1R,2S)-2-Amino-1,2-diphenylethanol
Benzyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate
트렌스-2-페닐비닐보로닉 엑시드
N-[(1S,2R)-2-Hydroxy-1,2-diphenylethyl]-glycine Ethyl Ester
2-Oxo-4-phenylbutyric acid
준비 용품
L-Homophe-OH 공급 업체
글로벌( 541)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| DONBOO AMINO ACID COMPANY | +8613063595538 |
donboo@donboo.com | China | 9365 | 58 |
| Sichuan HongRi Pharma-Tech Co.,Ltd | +86-028-64841719 +8618980456393 |
daisy@enlaibio.com | China | 1369 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12456 | 58 |
| Chongqing Zhihe Biopharmaceutical Co., Ltd. | +86-18580541567 +86-17782035140 |
sales@zhswyy.com | China | 338 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15928 | 58 |
| Taizhou Tianhong Biochemistry Technology Co., Ltd. | 0523-86132544 |
sales@thbiochem.com | CHINA | 305 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
L-Homophe-OH 관련 검색:
감마-아미노-N-부티르 산 DL-6,8-티옥트 산 L-(+)-아르기닌 글리신 베타인 L-알라닌
4-(4-Aminophenyl)butyric acid
Boc-D-Tyr-OH
4-Phenylbutyric acid
METHYL 4-(4-AMINOPHENYL)BUTANOATE
ALTRENOGEST
L-Homophenylalanine ethyl ester hydrochloride
2,4-DICHLORO-L-BETA-HOMOPHENYLALANINE HYDROCHLORIDE
[-/+]-2-AMINO-4-PHENYLBUTYRIC ACID,DL-ALPHA-AMINO-4-PHENYLBUTYRIC ACID
BOC-(S)-3-AMINO-4-(4-CHLORO-PHENYL)-BUTYRIC ACID
FMOC-4-TRIFLUOROMETHYL-D-BETA-HOMOPHENYLALANINE
Phenylacetone
N-[(tert-Butoxy)carbonyl]-D-tryptophan