2',5'-Dihydroxyacetophenone
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2',5'-Dihydroxyacetophenone 속성
- 녹는점
- 204-206 °C(lit.)
- 끓는 점
- 234.6°C (rough estimate)
- 밀도
- 1.2143 (rough estimate)
- 굴절률
- 1.4447 (estimate)
- 저장 조건
- Store below +30°C.
- 용해도
- 디옥산: 50mg/mL, 투명
- 물리적 상태
- 결정 또는 결정성 분말
- 산도 계수 (pKa)
- 9.86±0.18(Predicted)
- 색상
- 노란색에서 노란색-녹색
- 수용성
- 불용성
- BRN
- 637903
- InChIKey
- WLDWSGZHNBANIO-UHFFFAOYSA-N
- LogP
- 1.274 (est)
- CAS 데이터베이스
- 490-78-8(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38 | ||
| 안전지침서 | 26-36 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | AM7700000 | ||
| 위험 참고 사항 | Irritant | ||
| TSCA | Yes | ||
| HS 번호 | 29145000 |
2',5'-Dihydroxyacetophenone C화학적 특성, 용도, 생산
개요
2',5'-Dihydroxyacetophenone is a natural phenolic compound that is found in many plants. It has been shown to have anti-inflammatory properties through its ability to inhibit the production of pro-inflammatory cytokines, such as tumor necrosis factor alpha and interleukin 1 beta.화학적 성질
yellow to yellow-green crystals or용도
2',5'-Dihydroxyacetophenone is an intermediate used in various synthetic preparations of pharmaceutical goods, 1-(2,5-Dihydroxyphenyl)ethanone was untilized in the synthesis of new flavonoid fatty acid esters with anti-adipogenic and glucose consumption enhancing activities.제조 방법
Preparation by Fries rearrangement of hydroquinone diacetate,with aluminium chloride(91%) (76%)(63–77%) (55–60%)
with zinc chloride in refluxing acetic acid (quantitative yield)
with boron trifluoride etherate in benzene at reflux (65%).
주요 응용
2',5'-Dihydroxyacetophenone inhibits the formation of reactive oxygen species and nitric oxide in rat neutrophils. It also has the ability to reduce oxidative stress by scavenging free radicals and inhibiting lipid peroxidation. The underlying mechanism for these effects is not fully understood but may be due to its ability to act as a substrate for matrix-assisted laser desorption ionization (MALDI). This means that it can react with protocatechuic acid molecules that are present in the sample preparation chamber, leading to polymerase chain reaction (PCR) amplification.2',5'-Dihydroxyacetophenone 준비 용품 및 원자재
원자재
준비 용품
2',5'-Dihydroxyacetophenone 공급 업체
글로벌( 381)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88299272 |
info@edengenechem.com | China | 2169 | 58 |
| Xi'an Yutbon Pharmaceutical Technology Co., Ltd | 029-81140587 +8618717328141 |
sales@yutbon.com | China | 437 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12453 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15371 | 58 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | 18957127338 |
stella@zetchem.com | China | 2141 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 |
info@accelachem.com | United States | 19965 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8822 | 58 |
2',5'-Dihydroxyacetophenone 관련 검색:
히드록시아세토페논 아세토페논 2-히드록시아세토페논 4'-히드록시아세토페논 2,3-다이하이드로-9,10-다이하이드록시-1,4-안트라센디온 1,4-다이하이드록시안트라퀴논
2-Bromoacetophenone
PIPERACETAZINE (250 MG)
DIHYDROXYACETOPHENONE,DIHYDROXYACETOPHENONE,3,4-,3',4'-DIHYDROXYACETOPHENONE,3,4-DIHYDROXYACETOPHENONE,3,4-Dihydroxyacetophenone 3',4'-Dihydroxyacetophenone
4'-Bromoacetophenone
3'-Hydroxyacetophenone
3-Nitroacetophenone
2',4'-Dichloroacetophenone
3-Aminoacetophenone
4-Nitroacetophenone
2',6'-Dihydroxyacetophenone
3',5'-Dihydroxyacetophenone 3,5-Dihydroxyacetophenone,3',5'-DIHYDROXYACETOPHENONE,3,5-DIHYDROXYACETOPHENONE MONOHYDRATE,3,5-DIHYDROXYACETOPHENONE
2'-Hydroxy-5'-methoxyacetophenone