Bisoprolol
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Bisoprolol 속성
- 녹는점
- 100 °C
- 끓는 점
- 445.0±45.0 °C(Predicted)
- 밀도
- 1.033±0.06 g/cm3(Predicted)
- 저장 조건
- -20°C Freezer, Under Inert Atmosphere
- 용해도
- 클로로포름(소량으로 용해), 메탄올(약간 용해됨)
- 산도 계수 (pKa)
- pKa 9.57(H2O(extrap) t=25±1 Iunde?ned Aratmosphere) (Uncertain)
- 색상
- 노란색
- 수용성
- 5.5ug/L(100℃)
- CAS 데이터베이스
- 66722-44-9(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 22 | ||
| WGK 독일 | 1 | ||
| RTECS 번호 | UB8380000 | ||
| 위험 등급 | IRRITANT | ||
| 유해 물질 데이터 | 66722-44-9(Hazardous Substances Data) |
| 그림문자(GHS): |
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| 신호 어: | Warning | |||||||||||||||||||||
| 유해·위험 문구: |
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| 예방조치문구: |
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Bisoprolol C화학적 특성, 용도, 생산
화학적 성질
Yellow Oil용도
Cardensiel is an intermediate in the synthesis of 3,3''-(Isopropylazanediyl)bis(1-(4-((2-isopropoxyethoxy)methyl)phenoxy)propan-2-ol) (I824005), which is an impurtiy of Bisoprolol (B510500), a selective β-adrenergic blocker. Used as an antihypertensive.효소 저해제
This oral cardiospecific β-blocker (FWfree-base = 325.45 g/mol; CAS 66722- 44-9; IUPAC: (RS)-1-{4-[(2-isopropoxyethoxy)methyl]phenoxy}-3- (isopropylamino)propan-2-ol), also named Zebeta? (oral tablets as fumarate salt), selectively targets β1-adrenergic receptors, blocking epinephrine stimulation of β1-adrenoreceptors that are concentrated in the heart muscle cells and heart conduction tissue as well as kidney juxtaglomerular cells. Bisoprolol is used to treat hypertension, coronary heart disease, arrhythmias, ischemic heart diseases, and myocardial infarction after the acute event. Given such versatility, bisoprolol is understandably included in the World Health Organization's List of Essential Medicines. Pharmacokinetics: Bioavailability > 90%; Hepatic metabolism (50%) by CYP2D6 and CYP3A4; Biological t1/2 = 10-12 hours.Bisoprolol 준비 용품 및 원자재
원자재
준비 용품
Bisoprolol 공급 업체
글로벌( 115)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12456 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 |
sales03@chemcn.cn | China | 951 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
| SIMAGCHEM CORP | +86-13806087780 |
sale@simagchem.com | China | 17367 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 |
eric@witopchemical.com | China | 23556 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 |
info@afinechem.com | CHINA | 15377 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6393 | 58 |
Bisoprolol 관련 검색:
프로판 p-펜네티딘 다이에톡시메테인 에톡시퀸
acetic acid, triethoxy-, ethyl ester
Ethoxyethyne
2-Ethoxyphenol
Bisoprolol EP IMpurity B HeMifuMarate (Bisoprolol n-Propyl Derivative HeMifuMarate)
2-Propanol, 1,1'-[methylenebis(4,1-phenyleneoxy)]bis[3-[(1-methylethyl)amino]-
Dehydroxy Bisoprolol
Bisoprolol EP Impurity D DiHCl
4-ISOPROPOXYETHOXYMETHYL-1-HYDROXYBENZENE(FOR BISOPROLOL),4-Isopropoxyethoxymethylphenol (Bisoprolol)
BISOPROLOL HEMIFUMARATE,(+/-)-BISOPROLOL HEMIFUMARATE
S-(-)-BISOPROLOL
BISOPROLOL FUMARATE
Bisoprolol
BISOPROLOL HEMIFUMARATE SALT
R-(+)-BISOPROLOL